Evidence map›Paper›PMID 41010348›Full record

ArticleLife (Basel, Switzerland)2025

Therapeutic Plasma Exchange in Intensive Care Units-A 5-Year Multicenter Retrospective Study.

Daria Syguła, Paulina Kluszczyk, Wiktor Wagner, Michał Krawiec, Szymon Bialka, Ewa Trejnowska, Grzegorz Brozek, Magdalena Latos, Paweł Dubik, Piotr Palaczynski and 2 more

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Daria SygułaStudent Scientific Society, Department of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Medyków 14 St., 40-752 Katowice, Poland.ORCID 0009-0001-4782-1901
Paulina KluszczykStudent Scientific Society, Department of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Medyków 14 St., 40-752 Katowice, Poland.ORCID 0009-0003-5774-1758
Wiktor WagnerStudent Scientific Society, Department of Anaesthesiology and Critical Care, School of Medicine with Division of Dentistry in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0009-0000-6909-7523
Michał KrawiecStudent Scientific Society, University Department of Cardiac Anaesthesia and Intensive Care, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Szymon BialkaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0000-0002-5923-2469
Ewa TrejnowskaDepartment of Cardiac Anaesthesia and Intensive Care, Silesian Center for Heart Diseases in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Grzegorz BrozekDepartment of Epidemiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medyków 14 St., 40-752 Katowice, Poland.ORCID 0000-0002-0716-6471
Magdalena LatosDepartment of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0000-0002-6429-7638
Paweł DubikDepartment of Anesthesiology and Intensive Therapy, Healthcare Center of the Ministry of Internal Affairs and Administration Named After Sergeant Grzegorz Załoga, Wita Stwosza 39-41 St., 40-042 Katowice, Poland.
Piotr PalaczynskiDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Piotr KnapikDepartment of Cardiac Anaesthesia and Intensive Care, Silesian Center for Heart Diseases in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Szymon SkoczyńskiDepartment of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0000-0003-1796-7659

Funding

Medical University of Silesia in Poland BNW-1-105/N/5/K
6 · The paper itself

Abstract

(1).

backgroundTherapeutic plasma exchange (TPE) is a method of extracorporeal plasma filtration designed to remove immunoglobulins and pro-inflammatory factors as pathogenesis of numerous diseases. Procedures are performed in intensive care units (ICUs); however, the complications and treatment outcomes remain unclear. The aim of the study was to evaluate clinical outcomes and identify risk factors of complications associated with TPE. (2).

methodsIn this multi-center, retrospective, 5-year cohort study, we analyzed a database of 56 adult ICU patients who had undergone TPE at two academic hospitals and one regional hospital. (3).

resultsIn our study, the median APACHE II was 7.5 IQR 12.5 (4-16.5) and SOFA score was 2 IQR 4 (1-5). In the multivariate analysis, the APACHE II (

conclusionsOur results suggest that the SOFA and APACHE II scores are significant predictors of the length of hospitalization and the occurrence of shock. In addition, the SOFA score was a predictor of HAI in patients treated TPE in ICU.

Indexed as

APACHEcomplicationsintensive care units (ICU)SOFAtherapeutic plasma exchange (TPE)

Identifiers

PMID41010348
PMCPMC12470973

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.