ArticleLife (Basel, Switzerland)2025
Therapeutic Plasma Exchange in Intensive Care Units-A 5-Year Multicenter Retrospective Study.
Daria Syguła, Paulina Kluszczyk, Wiktor Wagner, Michał Krawiec, Szymon Bialka, Ewa Trejnowska, Grzegorz Brozek, Magdalena Latos, Paweł Dubik, Piotr Palaczynski and 2 more
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In one paragraphArticle in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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1 · What the graph read from itWhat it found
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
12 authors.
Daria SygułaStudent Scientific Society, Department of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Medyków 14 St., 40-752 Katowice, Poland.ORCID 0009-0001-4782-1901 Paulina KluszczykStudent Scientific Society, Department of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Medyków 14 St., 40-752 Katowice, Poland.ORCID 0009-0003-5774-1758 Wiktor WagnerStudent Scientific Society, Department of Anaesthesiology and Critical Care, School of Medicine with Division of Dentistry in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0009-0000-6909-7523 Michał KrawiecStudent Scientific Society, University Department of Cardiac Anaesthesia and Intensive Care, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Szymon BialkaDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0000-0002-5923-2469 Ewa TrejnowskaDepartment of Cardiac Anaesthesia and Intensive Care, Silesian Center for Heart Diseases in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Grzegorz BrozekDepartment of Epidemiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Medyków 14 St., 40-752 Katowice, Poland.ORCID 0000-0002-0716-6471 Magdalena LatosDepartment of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0000-0002-6429-7638 Paweł DubikDepartment of Anesthesiology and Intensive Therapy, Healthcare Center of the Ministry of Internal Affairs and Administration Named After Sergeant Grzegorz Załoga, Wita Stwosza 39-41 St., 40-042 Katowice, Poland.
Piotr PalaczynskiDepartment of Anaesthesiology and Intensive Therapy, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Piotr KnapikDepartment of Cardiac Anaesthesia and Intensive Care, Silesian Center for Heart Diseases in Zabrze, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.
Szymon SkoczyńskiDepartment of Lung Diseases and Tuberculosis, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Plac Traugutta 2 St., 41-800 Zabrze, Poland.ORCID 0000-0003-1796-7659 Funding
Medical University of Silesia in Poland BNW-1-105/N/5/K
6 · The paper itselfAbstract
(1).
backgroundTherapeutic plasma exchange (TPE) is a method of extracorporeal plasma filtration designed to remove immunoglobulins and pro-inflammatory factors as pathogenesis of numerous diseases. Procedures are performed in intensive care units (ICUs); however, the complications and treatment outcomes remain unclear. The aim of the study was to evaluate clinical outcomes and identify risk factors of complications associated with TPE. (2).
methodsIn this multi-center, retrospective, 5-year cohort study, we analyzed a database of 56 adult ICU patients who had undergone TPE at two academic hospitals and one regional hospital. (3).
resultsIn our study, the median APACHE II was 7.5 IQR 12.5 (4-16.5) and SOFA score was 2 IQR 4 (1-5). In the multivariate analysis, the APACHE II (
conclusionsOur results suggest that the SOFA and APACHE II scores are significant predictors of the length of hospitalization and the occurrence of shock. In addition, the SOFA score was a predictor of HAI in patients treated TPE in ICU.
Indexed as
APACHEcomplicationsintensive care units (ICU)SOFAtherapeutic plasma exchange (TPE)
Identifiers
PMID41010348
PMCPMC12470973
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