Evidence map›Paper›PMID 41010131›Full record

ArticleMaterials (Basel, Switzerland)2025

Failure Prediction of Lithium Disilicate and Composition-Gradient Multilayered Zirconia Occlusal Veneers: A Fractographic and Theoretical Analysis.

Lea S Prott, Petra C Gierthmuehlen, Markus B Blatz, Yu Zhang

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lea S ProttDepartment of Preventive and Restorative Sciences, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0003-0792-0830
Petra C GierthmuehlenDepartment of Prosthodontics, Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, 40225 Düsseldorf, Germany.ORCID 0000-0002-4837-2546
Markus B BlatzDepartment of Preventive and Restorative Sciences, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Yu ZhangDepartment of Preventive and Restorative Sciences, Penn Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Funding

Toward novel translucent and strong nanostructured dental zirconiaR01DE026772 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI ZHANG, YU · 2017 to 2021
$1.8M
Ultrafast sintering of dental zirconia: composition-processing-property relationships with high-throughput fail-fast screeningR01DE033545 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI Liangbing Hu, Yu Zhang · 2023 to 2026
$1.8M
Ivoclar Vivadent n/aNIDCR NIH HHS R01 DE026772NIDCR NIH HHS R01 DE033545NIH HHS 1R01DE026279-24NIH HHS 1R01DE033545-28
6 · The paper itself

Abstract

This in vitro study aimed to evaluate the fatigue behavior of occlusal veneers (OVs) made of lithium disilicate and composition-gradient multilayered zirconia at different thicknesses, incorporating both experimental and theoretical analyses to predict long-term performance. Seventy-two OVs with ceramic layer thicknesses of 0.5 mm, 1.0 mm, and 1.5 mm were fabricated and adhesively bonded to dentin analog composite abutments. All specimens underwent thermomechanical fatigue testing, involving cyclic loading (49 N, 1.6 Hz, 1.2 million cycles) and thermocycling (5-55 °C), simulating five years of clinical function. Fracture patterns were analyzed using light microscopy and scanning electron microscopy. A fatigue lifetime model based on plate-on-foundation theory and slow crack growth was applied to estimate cycles to radial failure. No complete fractures or debonding occurred. However, 50% of 0.5 mm zirconia OVs developed flexural radial cracks from the intaglio surface, while all lithium disilicate and zirconia veneers ≥1.0 mm remained intact. Theoretical predictions closely matched the experimental outcomes, indicating that 0.5 mm zirconia performance aligned with the lower-bound fatigue estimates for 5Y-PSZ. Results suggest that lithium disilicate offers superior fatigue resistance at minimal thickness, while thin zirconia is prone to subsurface cracking. A minimum thickness of 0.7 mm is recommended for zirconia-based OVs.

Indexed as

ceramic thicknessfatigue fracturefracture mechanicslithium disilicateocclusal veneerzirconia

Identifiers

PMID41010131
PMCPMC12471659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.