Evidence map›Paper›PMID 41009996›Full record

ArticleGenes2025

Comparative Genomics and Functional Profiling Reveal Lineage-Specific Metabolic Adaptations in Globally Emerging Fluoroquinolone-Resistant

Juned Ahmed, Rachel C Soltys, Smriti Shringi, Jean Guard, Bradd J Haley, Devendra H Shah

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Genomic characterization ofFrontiers in veterinary science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juned AhmedSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0000-0003-3904-9381
Rachel C SoltysAnimal Disease Diagnostic Laboratory, Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, IN 47907, USA.ORCID 0000-0003-0916-3597
Smriti ShringiSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0000-0001-9212-9175
Jean GuardUnited States National Poultry Research Center, Agriculture Research Service, United States Department of Agriculture, Athens, GA 30605, USA.ORCID 0000-0003-3968-4705
Bradd J HaleyEnvironmental Microbial and Food Safety Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705, USA.ORCID 0000-0001-7996-1143
Devendra H ShahSchool of Veterinary Medicine, Texas Tech University, Amarillo, TX 79106, USA.ORCID 0000-0001-6365-7868

Funding

U.S. National Poultry Research Center, Agriculture Research Service, U.S. Department of Agriculture. 6040-32000-011-05J
6 · The paper itself

Abstract

background

methodsWe performed comparative metabolic profiling of ST198 (

resultsST198 exhibited significantly higher respiratory activity and broader metabolic versatility across carbon, nitrogen/sulfur sources, and stress conditions. The canonical

conclusionsThese findings highlight ST198's metabolic adaptability and reveal novel metabolic capacities in NTS. A mechanistic understanding of nutrient utilization pathways, particularly of

Indexed as

Adaptation, PhysiologicalDrug Resistance, BacterialFluoroquinolonesSalmonellaAnimalsAnti-Bacterial AgentsGenome, BacterialGenomicsHumansInositolSalmonella InfectionsAnti-Bacterial AgentsFluoroquinolonesInositolmetabolismSalmonella KentuckyST152ST198

Identifiers

PMID41009996
PMCPMC12469290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.