Evidence map›Paper›PMID 41009934›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Retargeting Gram-Positive-Only Adarotene-Derived Antibacterials to Broad-Spectrum Antibiotics.

Salvatore Princiotto, Luigi Cutarella, Alessandra Fortuna, Marta Mellini, Bruno Casciaro, Maria Rosa Loffredo, Alvaro G Temprano, Floriana Cappiello, Livia Leoni, Maria Luisa Mangoni and 7 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Salvatore PrinciottoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.ORCID 0000-0003-3440-8373
Luigi CutarellaDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.ORCID 0009-0004-9789-8060
Alessandra FortunaDepartment of Science, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.ORCID 0000-0003-3433-8328
Marta MelliniDepartment of Science, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.ORCID 0000-0003-0423-6734
Bruno CasciaroLaboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-1295-1084
Maria Rosa LoffredoLaboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0001-5040-5688
Alvaro G TempranoDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.ORCID 0000-0002-5478-5937
Floriana CappielloLaboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0003-3423-8474
Livia LeoniDepartment of Science, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.ORCID 0000-0002-2046-4297
Maria Luisa MangoniLaboratory affiliated to Pasteur Italia-Fondazione Cenci Bolognetti, Department of Biochemical Sciences, Sapienza University of Rome, 00185 Rome, Italy.ORCID 0000-0002-5991-5868
Mattia MoriDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, via Aldo Moro 2, 53100 Siena, Italy.ORCID 0000-0003-2398-1254
Loana MussoDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-6838-7753
Francesca SacchiDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-3973-0989
Cecilia PinnaDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-2828-5875
Giordano RampioniDepartment of Science, University Roma Tre, Viale G. Marconi 446, 00146 Rome, Italy.ORCID 0000-0002-1735-8565
Sabrina DallavalleDepartment of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, via Celoria 2, 20133 Milan, Italy.ORCID 0000-0002-8813-8922
Claudio PisanoSpecial Products Line, 03012 Anagni, Italy.ORCID 0000-0001-8624-2980

Funding

European Union NextGenerationEU B83C22002820006European Union NextGenerationEU F83B22000040006Ministero dell'università e della ricerca 202089LLEHMinistero dell'università e della ricerca 20224BYR59Ministero dell'università e della ricerca 2022C5PNXBMinistero dell'università e della ricerca PE00000007
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adaroteneantibacterialbroad-spectrumGram-negativeGram-positivemultidrug-resistanceouter membrane

Identifiers

PMID41009934
PMCPMC12466880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.