Evidence map›Paper›PMID 41009878›Full record

ArticleAntibiotics (Basel, Switzerland)2025

Antimicrobial Resistance Profiles of Clinically Relevant Enterobacteriaceae Isolates: A Retrospective Study at a Southern Italian Hospital.

Giorgia Stornelli, Beatrice Marinacci, Valentina Puca, Benedetta Pellegrini, Roberta Zita Marulli, Ivana Cataldo, Francesca Sisto, Vittoria Perrotti, Arianna Pompilio, Mattia Mori and 2 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Giorgia StornelliDepartment of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Beatrice MarinacciDepartment of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0009-0005-7069-5914
Valentina PucaDepartment of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-6417-876X
Benedetta PellegriniDepartment of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0009-0000-1564-9062
Roberta Zita MarulliOperative Unit of Clinical Pathology, S. Pio Hospital, 66054 Chieti, Italy.
Ivana CataldoOperative Unit of Clinical Pathology, S. Pio Hospital, 66054 Chieti, Italy.
Francesca SistoDepartment of Biomedical, Surgical and Dentistry Sciences, University of Milano, 20133 Milano, Italy.ORCID 0000-0003-0166-2164
Vittoria PerrottiDepartment of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0001-7652-1660
Arianna PompilioDepartment of Medical, Oral and Biotechnological Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-6309-6981
Mattia MoriDepartment of Biotechnology, Chemistry and Pharmacy, University of Siena, Via Aldo Moro 2, 53100 Siena, Italy.ORCID 0000-0003-2398-1254
Pamela Di GiovanniDepartment of Medicine and Ageing Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-6448-8960
Rossella GrandeDepartment of Pharmacy, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-8432-6889

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Enterobacteriaceae family is the most heterogeneous group of Gram-negative bacilli, with both environmental and clinical relevance. Although many of these species are part of the normal intestinal microbiota, species such as

methodsA retrospective analysis was carried out on biological samples collected between 2019 and 2023 at the Microbiology Laboratory of the San Pio Hospital, Vasto (Italy). Eight hundred ninety patients were included, with an average age of 73 years. Bacterial identification was carried out using bacterial culture and biochemical methods, while antimicrobial sensitivity was assessed by using the automated Walk Away System.

resultsThe most frequently isolated species were

conclusionsThe high prevalence of antimicrobial resistance among clinically relevant Enterobacteriaceae species is a growing clinical challenge. The results of this study, which describe the trend of resistance among Enterobacteriaceae in a local hospital, could help to raise awareness highlighting the urgent need for more advanced diagnostic tools and new therapeutic strategies to treat infections caused by multi-resistant microorganisms.

Indexed as

antimicrobial resistancecarbapenemase-producing bacteriaEnterobacteriaceaeEscherichia coliextended-spectrum beta-lactamaseKlebsiella pneumoniaenosocomial infectionsProteus mirabilisretrospective study

Identifiers

PMID41009878
PMCPMC12466627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.