Evidence map›Paper›PMID 41009857›Full record

ArticleAntibiotics (Basel, Switzerland)2025

AdpA, a Global Regulator of Hundreds of Genes, Including Those for Secondary Metabolism, in

Marcin Wolański, Małgorzata Płachetka, Volha Naumouskaya, Agnieszka Strzałka, Michał Tracz, Diana Valietova, Jolanta Zakrzewska-Czerwińska

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marcin WolańskiFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.ORCID 0000-0003-4714-0716
Małgorzata PłachetkaFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
Volha NaumouskayaFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
Agnieszka StrzałkaFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
Michał TraczFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
Diana ValietovaFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.
Jolanta Zakrzewska-CzerwińskaFaculty of Biotechnology, University of Wrocław, 50-383 Wrocław, Poland.

Funding

"Excellence Initiative - Research University" (IDUB) program for the University of Wrocław BPIDUB.11.2023National Science Center Miniatura 2019/03/X/NZ1/00280
6 · The paper itself

Abstract

background

methodsWe applied RNA-seq and ChIP-seq at 12 and 20 h-corresponding to vegetative and aerial hyphae stages-to profile the AdpA

resultsAdpA

conclusionsThis study defines, for the first time, the direct AdpA regulon in

Indexed as

ChIP-seqgene expressionRNA-seqsecondary metabolite gene cluster/secondary metabolitesStreptomyces venezuelaetranscriptional regulator

Identifiers

PMID41009857
PMCPMC12466573

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.