Evidence map›Paper›PMID 41009782›Full record

ArticleInternational journal of molecular sciences2025

Progressive Ocular Axial Elongation and Retinal Ganglion Cell Degeneration in Mice with Elastic Fiber Disorder.

Samuel Insignares, John Kuchtey, Rachel W Kuchtey

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Samuel InsignaresVanderbilt Eye Institute, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN 37232, USA.ORCID 0009-0003-6778-3329
John KuchteyVanderbilt Eye Institute, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN 37232, USA.
Rachel W KuchteyVanderbilt Eye Institute, Vanderbilt University Medical Center, 2311 Pierce Avenue, Nashville, TN 37232, USA.

Funding

Shop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6M
Targeting Tissue Biomechanics for Treatment of GlaucomaR01EY020894 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KUCHTEY, RACHEL W · 2010 to 2025
$6.4M
NEI NIH HHS P30 EY008126NEI NIH HHS R01 EY020894NEI NIH HHS R01EY020894
6 · The paper itself

Abstract

We previously reported ocular phenotypes of 1-year-old 129S1/SvlmJ lysyl oxidase-like 1 null (

Indexed as

Elastic TissueRetinal DegenerationRetinal Ganglion CellsAmino Acid OxidoreductasesAnimalsDisease Models, AnimalElectroretinographyMiceMice, Inbred C57BLMice, KnockoutOptic NerveTomography, Optical CoherenceAmino Acid OxidoreductasesLoxl1 protein, mouseelastic fiber disorderglaucomamyopia

Identifiers

PMID41009782
PMCPMC12471019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.