Evidence map›Paper›PMID 41009778›Full record

ReviewInternational journal of molecular sciences2025

Potential of Orally Administered Quercetin, Hesperidin, and

Takanobu Takata, Junji Moriya, Katsuhito Miyazawa, Sohsuke Yamada, Jia Han, Qian Yang, Xin Guo, Takeshi Nakahashi, Shuichi Mizuta, Shinya Inoue and 2 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takanobu TakataDivision of Molecular and Genetic Biology, Department of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.ORCID 0000-0003-0514-8584
Junji MoriyaDepartment of General Internal Medicine, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.
Katsuhito MiyazawaDepartment of Urology, Kanazawa Medical University Hospital, Uchinada 920-0393, Ishikawa, Japan.ORCID 0000-0002-0331-3753
Sohsuke YamadaDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.ORCID 0000-0003-2662-0024
Jia HanDepartment of Pathology and Laboratory Medicine, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.ORCID 0000-0003-0108-996X
Qian YangDepartment of Spleen and Stomach Diseases, First Affiliated Hospital of Hebei University of Chinese Medicine, Shijiazhuang 050011, China.ORCID 0000-0002-0250-7556
Xin GuoHebei Key Laboratory of Turbidity Toxin Syndrome, Shijiazhuang 050011, China.
Takeshi NakahashiDepartment of General Internal Medicine, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.
Shuichi MizutaDepartment of General Internal Medicine, Kanazawa Medical University, Uchinada 920-0293, Ishikawa, Japan.ORCID 0000-0001-6690-5409
Shinya InoueDepartment of Urology, Kanazawa Medical University Hospital, Uchinada 920-0393, Ishikawa, Japan.ORCID 0000-0001-8639-6955
Togen MasaujiDepartment of Pharmacy, Kanazawa Medical University Hospital, Uchinada 920-0293, Ishikawa, Japan.ORCID 0009-0000-5897-8800
Yoshiharu MotooDepartment of Internal Medicine, Fukui Saiseikai Hospital, Wadanaka 918-8503, Fukui, Japan.

Funding

Japan Society for the Promotion of Science JP24K14802
6 · The paper itself

Abstract

Advanced glycation end-products (AGEs) are associated with the dysfunction of proximal tubular epithelial (PTE) cells in lifestyle diseases. Urinary stones induce cytotoxicity in PTE cells, and various medicines have been developed to mitigate or prevent their generation/accumulation. The leaves of

Indexed as

Coumaric AcidsEpithelial CellsGlycation End Products, AdvancedHesperidinKidney Tubules, ProximalQuercetinAdministration, OralAnimalsHumansPropionatesCoumaric AcidsGlycation End Products, AdvancedHesperidinp-coumaric acidPropionatesQuercetinadvanced glycation end-producthesperidinmetabolismp-coumaric acidproximal tubular epithelial cellquercetinQuercus salicina BlumeQuercus stenophylla Makinotraditional Japanese medicine

Identifiers

PMID41009778
PMCPMC12471064

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.