Evidence map›Paper›PMID 41009774›Full record

ArticleInternational journal of molecular sciences2025

Synthesis of Novel Tricyclic N-Acylhydrazones as Tubulin Polymerization Inhibitors.

Paola Corona, Michele Lai, Battistina Asproni, Giulia Sciandrone, Ilenia Lupinu, Roberta Ibba, Sandra Piras, Antonio Carta, Gabriele Murineddu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Tricyclic Pyrrole-Based Compounds as Zika Virus Inhibitors.International journal of molecular sciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paola CoronaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-9182-478X
Michele LaiRetrovirus Centre, Department of Translational Medicine and New Technologies in Medicine and Surgery, University of Pisa, 56127 Pisa, Italy.ORCID 0000-0001-7597-123X
Battistina AsproniDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-0988-1882
Giulia SciandroneDepartment of Medical Biotechnologies, University of Siena, 53100 Siena, Italy.
Ilenia LupinuDepartment of Chemical, Physical, Mathematical and Natural Sciences, University of Sassari, 07100 Sassari, Italy.
Roberta IbbaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0003-3332-3845
Sandra PirasDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Antonio CartaDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Gabriele MurinedduDepartment of Medicine, Surgery and Pharmacy, University of Sassari, 07100 Sassari, Italy.ORCID 0000-0002-2791-9178

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of

Indexed as

Antineoplastic AgentsHydrazonesTubulinTubulin ModulatorsCell Line, TumorCell ProliferationHumansPolymerizationStructure-Activity RelationshipAntineoplastic AgentsHydrazonesTubulinTubulin Modulators1,4-dihydroindeno[1,2-b]pyrrole-3-carbohydrazidesA375 cell lineantiproliferative and cytotoxic activitymolecular dockingβ-tubulin inhibitors

Identifiers

PMID41009774
PMCPMC12470774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.