Evidence map›Paper›PMID 41009679›Full record

ArticleInternational journal of molecular sciences2025

Increasing Temperature Activates TREK Potassium Currents in Vagal Afferent Neurons from the Nodose Ganglion.

Lola Rueda-Ruzafa, Ana Campos-Ríos, Paula Rivas-Ramírez, Manuela Rodríguez-Castañeda, Salvador Herrera-Pérez, José Antonio Lamas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lola Rueda-RuzafaDepartment of Functional Biology and Health Sciences, University of Vigo, 36310 Vigo, Spain.ORCID 0000-0002-0151-8018
Ana Campos-RíosDepartment of Functional Biology and Health Sciences, University of Vigo, 36310 Vigo, Spain.ORCID 0000-0002-7765-6345
Paula Rivas-RamírezDepartment of Functional Biology and Health Sciences, University of Vigo, 36310 Vigo, Spain.
Manuela Rodríguez-CastañedaDepartment of Functional Biology and Health Sciences, University of Vigo, 36310 Vigo, Spain.ORCID 0000-0002-5977-6845
Salvador Herrera-PérezDepartment of Functional Biology and Health Sciences, University of Vigo, 36310 Vigo, Spain.ORCID 0000-0002-0491-3718
José Antonio LamasDepartment of Functional Biology and Health Sciences, University of Vigo, 36310 Vigo, Spain.

Funding

Ministerio de Ciencia, Innovación y Universidades PID2022-138236NB-I00Xunta de Galicia ED481A-2022Xunta de Galicia GPC2015/022
6 · The paper itself

Abstract

Temperature homeostasis is controlled by the vagus nerve. Thermal information is collected by thermoreceptors present in the viscera and driven across sensory neurons of the nodose ganglia (NG), which in turn send it to the hypothalamus. While transient receptor potential channels (TRPs) are traditionally considered for thermal transduction, TREK channels belonging to the two-pore domain K

Indexed as

Neurons, AfferentNodose GanglionPotassium Channels, Tandem Pore DomainVagus NerveAnimalsMaleMembrane PotentialsMicePatch-Clamp TechniquesTemperaturepotassium channel protein TREK-1Potassium Channels, Tandem Pore Domaininternal temperatureK2P channelsneuronal excitabilitynodose ganglionpatch-clamppotassium channelstemperaturethermal homeostasisTREK channelsvagus nerve

Identifiers

PMID41009679
PMCPMC12470281

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.