ArticleInternational journal of molecular sciences2025
Development of a Raman-Based Method for the Diagnosis of People with Obstructive Sleep Apnea Syndrome: The Role of Lactic Acid.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Raman Spectroscopy for Probing Pathological Protein Aggregates: Potential and Perspectives for Advanced Diagnostic Applications.International journal of molecular sciences · 2026Review
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Authors and funding
7 authors.
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Abstract
Obstructive sleep apnea syndrome (OSAS) is a respiratory disorder in middle-aged and elderly populations, marked by breathing interruptions during sleep. Diagnosis faces challenges due to the absence of specific biomarkers and increasing screening demands. This study aims to identify salivary biomarkers for the diagnosis and monitoring of OSAS using a simplified, rapid, and non-invasive method. Saliva from 51 OSAS patients and 34 healthy controls (CTR) was analyzed using Raman spectroscopy, which identified disease-specific biochemical fingerprints. Raman analysis revealed differences between the OSAS and CTR groups. The area under the curve of the lactic acid peak (920 cm
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