Evidence map›Paper›PMID 41009645›Full record

ArticleInternational journal of molecular sciences2025

Translational Evaluation of an Intraparenchymal Collagen Matrix Tamponade: Initial Preclinical and Clinical Experiments to Prevent CSF Reflux Following Endoscopic Brain Surgery.

Yasuo Aihara, Kentaro Chiba, Yuichi Oda, Kevin Browne, Dmitriy Petrov, Takakazu Kawamata, John C O'Donnell

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yasuo AiharaDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.ORCID 0000-0002-4837-6248
Kentaro ChibaDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Yuichi OdaDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.
Kevin BrowneCenter for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0002-5604-3021
Dmitriy PetrovCenter for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Takakazu KawamataDepartment of Neurosurgery, Tokyo Women's Medical University, Tokyo 162-8666, Japan.ORCID 0000-0002-6076-7065
John C O'DonnellCenter for Brain Injury & Repair, Department of Neurosurgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-8101-3783

Funding

RRD VA IK2 RX003376
6 · The paper itself

Abstract

Transparent polymer sheaths are often utilized in neuroendoscopic procedures to minimize intraventricular bleeding and parenchymal injuries. However, cerebrospinal fluid (CSF) leakage remains a common complication following neuroendoscopic surgery for intraventricular and deep-seated lesions. We investigated an innovative technique to prevent postoperative CSF leakage through the tract using a collagen matrix dural graft. A rolled collagen matrix (DuraGen

Indexed as

BrainCerebrospinal Fluid LeakCollagenNeuroendoscopyAnimalsEndoscopyFemaleHumansMagnetic Resonance ImagingMalePilot ProjectsPostoperative ComplicationsSwineCollagencerebrospinal fluid leakDuraGeninflammationneuroendoscopeparenchymal tractregenerative healing

Identifiers

PMID41009645
PMCPMC12471225

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.