ArticleInternational journal of molecular sciences2025
Circulating Plasma Syncytin-1 mRNA in Preeclampsia-A Pilot Study.
Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Evolutionary co-option of endogenous retroviruses: syncytins as regulators of placental development and disease.Molecular biology reports · 2026Review
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The endogenous human retroviral protein syncytin-1 is vital for placental integrity via syncytiotrophoblast formation. Preeclampsia has been associated with reduced placental syncytin-1 expression. The goal of the prospective pilot study was to investigate the role of circulating fetal syncytin-1 mRNA in women with and without preeclampsia (PE). We therefore determined syncytin-1 mRNA in maternal plasma of n = 26 women without and n = 43 women with PE with quantitative real-time PCR. Median circulating syncytin-1 mRNA concentrations were significantly lower in women with PE [1 217 050 copies; IQR 610 900-1 482 069] vs. those without PE [1 992 739 copies; IQR 1 616 811-3 126 225],
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