Evidence map›Paper›PMID 41009459›Full record

ArticleInternational journal of molecular sciences2025

Effects of Cherry Consumption on Metabolic Health: A Pilot Clinical Study on Healthy Adults.

Filomena Carvalho, Alexandra Varges, Radhia Aitfella Lahlou, Eduardo Bárbara, Isa Santos, Cecília Fonseca, Luís R Silva

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Filomena CarvalhoSPRINT-Sport Physical Activity and Health Research & Innovation Center, Polytechnic of Guarda, 6300-559 Guarda, Portugal.ORCID 0000-0002-0446-9020
Alexandra VargesSPRINT-Sport Physical Activity and Health Research & Innovation Center, Polytechnic of Guarda, 6300-559 Guarda, Portugal.
Radhia Aitfella LahlouSPRINT-Sport Physical Activity and Health Research & Innovation Center, Polytechnic of Guarda, 6300-559 Guarda, Portugal.ORCID 0000-0002-6911-6947
Eduardo BárbaraFamily Health Unit-Carolina Beatriz Ângelo, Local Health Unit of Guarda, 6300-035 Guarda, Portugal.
Isa SantosFamily Health Unit-A Ribeirinha, Local Health Unit of Guarda, 6300-690 Guarda, Portugal.
Cecília FonsecaIPG, Polytechnic of Guarda, 6300-559 Guarda, Portugal.ORCID 0000-0002-8543-331X
Luís R SilvaSPRINT-Sport Physical Activity and Health Research & Innovation Center, Polytechnic of Guarda, 6300-559 Guarda, Portugal.ORCID 0000-0001-5264-3516

Funding

Fundação para a Ciência e Tecnologia PD21-00023La Caixa Foundation PD21-00023PRR PRR-C05-i03-I-000143
6 · The paper itself

Abstract

Cherry consumption has been associated with several metabolic health benefits, due to their rich profile of bioactive compounds, including anthocyanins. This pilot clinical study, which is, to our knowledge, the first evaluating consumption of whole cherries, aimed to evaluate the effects of daily cherry consumption on oxidative stress, inflammation, glycaemic regulation, and other metabolic health markers in healthy adults. A total of 27 volunteers consumed 280 g of sweet cherries daily for 42 days, followed by a two-week post-intervention period. Significant improvements were observed in glucose regulation, including reduced HbA1c and estimated average glucose levels. Markers of inflammation, such as IL-6 and AGP-1 were significantly reduced during the intervention period. In addition, reductions in GGT and LDH indicated potential hepatoprotective effects. These results suggest that regular cherry consumption may serve as a preventive strategy against early metabolic dysfunction, highlighting the need for further investigation with larger, long-term clinical trials.

Indexed as

Prunus aviumAdultBiomarkersBlood GlucoseFemaleGlycated HemoglobinHealthy VolunteersHumansInflammationMaleMiddle AgedOxidative StressPilot ProjectsYoung AdultBiomarkersBlood GlucoseGlycated Hemoglobinanti-inflammatoryantioxidantcherry consumptionmetabolic healthphenolic compounds

Identifiers

PMID41009459
PMCPMC12470207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.