Floaters as the First Manifestation of Chronic Myeloid Leukemia: A Case Report.

Abstract readCase Reports

In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Siyun LeeDepartment of Ophthalmology, CHA Bundang Medical Center, CHA University School of Medicine, #59 Yatap-ro, Bundang-gu, Seongnam 13496, Republic of Korea.

Joonhyung KimDepartment of Ophthalmology, CHA Bundang Medical Center, CHA University School of Medicine, #59 Yatap-ro, Bundang-gu, Seongnam 13496, Republic of Korea.ORCID 0000-0002-3717-2223

Funding

Korean Association of Retinal Degeneration none

6 · The paper itself

Abstract

Chronic myeloid leukemia (CML) is a clonal myeloproliferative neoplasm arising in hematopoietic stem cells. It may initially present with ocular symptoms, as illustrated by the case of a previously healthy 25-year-old woman who presented with a five-day history of floaters in her left eye. Fundus examination revealed bilateral retinal hemorrhages, Roth spots, increased vascular tortuosity, a left preretinal hemorrhage, and a left vitreous hemorrhage. Retinopathy secondary to a hematologic disorder was considered; the patient was promptly referred to hematology-oncology. Laboratory evaluation demonstrated leukocytosis with anemia, peripheral smear showed 1% myeloblasts, 40% myelocytes, and basophilia. Cytogenetic analysis confirmed t(9;22)(q34;q11.2), and quantitative polymerase chain reaction (PCR) detected a

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveAdultFemaleFusion Proteins, bcr-ablHumansRetinal HemorrhageFusion Proteins, bcr-ablchronic myeloid leukemiafloaterleukemic retinopathyRoth spot

Identifiers

PMID41009410

DOI10.3390/ijms26188841

PMCPMC12469411

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.