Evidence map›Paper›PMID 41009388›Full record

ArticleInternational journal of molecular sciences2025

Neuroprotective Effects of Low-Dose Graphenic Materials on SN4741 Embryonic Stem Cells Against ER Stress and MPTP-Induced Oxidative Stress.

David Vallejo Perez, Monica Navarro, Beatriz Segura-Segura, Rune Wendelbo, Sara Bandrés-Ciga, Miguel A Arraez, Cinta Arraez, Noela Rodriguez-Losada

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

David Vallejo PerezNeurosurgery Unit, Biomedicine Research Institute of Malaga (IBIMA), Department of Neurosurgery, Málaga Regional University Hospital, 29010 Malaga, Spain.
Monica NavarroCatedra de Fisiologia, Facultad de Farmacia y Bioquimica, Universidad de Buenos Aires, Buenos Aires 1113, Argentina.ORCID 0009-0002-8393-6623
Beatriz Segura-SeguraVaccine Research Department, Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunidad Valenciana (FISABIO), 46024 Valencia, Spain.ORCID 0009-0007-5591-4319
Rune WendelboShift Materials AS, 0663 Oslo, Norway.
Sara Bandrés-CigaCenter for Alzheimer's and Related Dementias (CARD), National Institute on Aging and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.
Miguel A ArraezNeurosurgery Unit, Biomedicine Research Institute of Malaga (IBIMA), Department of Neurosurgery, Málaga Regional University Hospital, 29010 Malaga, Spain.
Cinta ArraezNeurosurgery Unit, Biomedicine Research Institute of Malaga (IBIMA), Department of Neurosurgery, Málaga Regional University Hospital, 29010 Malaga, Spain.
Noela Rodriguez-LosadaFaculty of Science Education, Department of Didactic Science Education, University of Malaga, 29010 Malaga, Spain.ORCID 0000-0003-3629-4883

Funding

Sponsorship Chair for Advanced Neurosurgery, University of Malaga. 00001University of Malaga, Campus de Excelencia Internacional Andalucía Tech, and Andalusian Government PAIDI-CTS156
6 · The paper itself

Abstract

In this study, we explore the neuroprotective and modulatory potential of graphenic materials (GMs) in terms of the maturation of dopaminergic neurons and their capacity to counteract the cellular stress induced by toxins such as MPP

Indexed as

Endoplasmic Reticulum StressGraphiteNeuroprotective AgentsOxidative Stress1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine1-Methyl-4-phenylpyridiniumalpha-SynucleinAnimalsCell LineDopaminergic NeuronsEndoplasmic Reticulum Chaperone BiPMiceMitochondriaTunicamycin1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine1-Methyl-4-phenylpyridiniumalpha-SynucleinEndoplasmic Reticulum Chaperone BiPgraphene oxideGraphiteHspa5 protein, mouseNeuroprotective AgentsTunicamyciner-stressgraphene oxidegraphene reducedneurodegenerative diseasesneuroprotectionparkinson’s disease

Identifiers

PMID41009388
PMCPMC12469652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.