Evidence map›Paper›PMID 41009333›Full record

ArticleInternational journal of molecular sciences2025

KRAS Copy Number Gain in Cell-Free DNA Analysis-Based Liquid Biopsy of Plasma and Bile in Patients with Various Pancreatic Neoplasms.

Mark Jain, David Atayan, Tagir Rakhmatullin, Tatiana Dakhtler, Victoria Inokenteva, Pavel Popov, Aleksandr Farmanov, Mikhail Viborniy, Iuliia Gontareva, Larisa Samokhodskaya and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mark JainUniversity Clinic, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0000-0002-6594-8113
David AtayanJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Tagir RakhmatullinUniversity Clinic, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0000-0002-4601-3478
Tatiana DakhtlerJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Victoria InokentevaUniversity Clinic, Lomonosov Moscow State University, 119992 Moscow, Russia.ORCID 0009-0003-5388-4356
Pavel PopovJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.ORCID 0000-0003-3300-7076
Aleksandr FarmanovJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.
Mikhail ViborniyJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.ORCID 0000-0001-6551-8810
Iuliia GontarevaJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.ORCID 0000-0003-4900-8997
Larisa SamokhodskayaUniversity Clinic, Lomonosov Moscow State University, 119992 Moscow, Russia.
Vyacheslav EgorovJoint Stock Company "Ilyinsky Hospital", 143421 Moscow, Russia.

Funding

Lomonosov Moscow State University State assignment
6 · The paper itself

Abstract

Cell-free DNA (cfDNA) analysis-based liquid biopsy is a rapidly emerging diagnostic and prognostic tool in pancreatic ductal adenocarcinoma (PDAC).

Indexed as

BileCarcinoma, Pancreatic DuctalCell-Free Nucleic AcidsDNA Copy Number VariationsPancreatic NeoplasmsProto-Oncogene Proteins p21(ras)AdultAgedAged, 80 and overBiomarkers, TumorFemaleHumansLiquid BiopsyMaleMiddle AgedPrognosisBiomarkers, TumorCell-Free Nucleic AcidsKRAS protein, humanProto-Oncogene Proteins p21(ras)bilecell-free DNAcopy number gaincopy number variationintraductal papillary–mucinous neoplasmKRASliquid biopsypancreatic cancerpancreatic ductal adenocarcinoma

Identifiers

PMID41009333
PMCPMC12469631

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.