Evidence map›Paper›PMID 41008924›Full record

ReviewCancers2025

The Usefulness of Indocyanine Green in Modern Gynecological Oncology-Analysis, Literature Review, and Future Perspectives.

Michał Kostrzanowski, Grzegorz Ziółkowski, Agata Mandes, Grzegorz Panek, Michał Ciebiera, Filip Dąbrowski

Abstract readReview
In one paragraph

Review in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michał KostrzanowskiDepartment of Gynecology and Gynecologic Oncology, Center of Postgraduate Medical Education, Cegłowska 80, 01-809 Warsaw, Poland.ORCID 0000-0001-8242-0428
Grzegorz ZiółkowskiDepartment of Gynecology and Gynecologic Oncology, Center of Postgraduate Medical Education, Cegłowska 80, 01-809 Warsaw, Poland.
Agata MandesDepartment of Gynecology and Gynecologic Oncology, Center of Postgraduate Medical Education, Cegłowska 80, 01-809 Warsaw, Poland.
Grzegorz PanekDepartment of Gynecology and Gynecologic Oncology, Center of Postgraduate Medical Education, Cegłowska 80, 01-809 Warsaw, Poland.
Michał CiebieraSecond Department of Obstetrics and Gynecology, Center of Postgraduate Medical Education, 00-189 Warsaw, Poland.ORCID 0000-0001-5780-5983
Filip DąbrowskiDepartment of Gynecology and Gynecologic Oncology, Center of Postgraduate Medical Education, Cegłowska 80, 01-809 Warsaw, Poland.ORCID 0000-0002-8557-4091

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indocyanine green (ICG) is a fluorescent agent which is characterized by a wide range of applications in the proper visualization of the operating field, differentiation of vital structures, and localization of lesions to be excised. An investigation and overview of novel approaches of indocyanine green in modern gynecological oncology was conducted, including ovarian cancer surgery with its compartmental approach and compartmental surgery in endometrial cancer. Ureteral visualization and perfusion, lymphography, lymph node transfers, or the localization of anastomotic leakage in bowel surgery are examples of applications aimed at reducing the risk of surgical complications and improving the patients' quality of life. The general use of indocyanine green in lymph node detection, subcategorized and analyzed, is constantly improved and reviewed. A therapeutic approach with macromolecules is being tested in preclinical models. Early results could suggest the future application of indocyanine green not only in broad-sense imaging but also as a cytotoxic agent conjugated with macromolecules. Further studies on the application of indocyanine green in laparoscopy, open surgery, and finally as a curative cytotoxic agent are needed.

Indexed as

compartmental surgeryfluorescenceimage-guided surgeryindocyanine greenlymphadenectomyprecision surgery

Identifiers

PMID41008924
PMCPMC12468064

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.