Evidence map›Paper›PMID 41008743›Full record

ReviewDiagnostics (Basel, Switzerland)2025

How to Perform Cardiac Contrast-Enhanced Ultrasound (cCEUS): Part II-Advanced Applications and Interpretation.

Harald Becher, Andreas Helfen, Guido Michels, Nicola Gaibazzi, Roxy Senior, Christoph Frank Dietrich

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Harald BecherMazankowski Alberta Heart Institute, Edmonton, AB T6G 2B7, Canada.
Andreas HelfenSt. Marien Hospital, 44534 Lünen, Germany.ORCID 0000-0002-3921-3594
Guido MichelsNotfallzentrum, Krankenhaus der Barmherzigen Brüder Trier, 54292 Trier, Germany.
Nicola GaibazziDepartment of Cardiology, University of Parma, 43121 Parma, Italy.
Roxy SeniorRoyal Brompton Hospital, National Heart and Lung Institute, Imperial College, London SW7 2AZ, UK.
Christoph Frank DietrichDepartment General Internal Medicine (DAIM), Hospitals Hirslanden Bern Beau Site, Salem and Permanence, 3013 Bern, Switzerland.ORCID 0000-0001-6015-6347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound enhancing agents (UEAs, formerly called contrast agents) have enhanced echocardiographic diagnostics of myocardial disease and masses as well as myocardial perfusion abnormalities. This review provides up-to-date guidance on the procedures and interpretations according to current recommendations of imaging societies and considering the results of recent major studies. For the different indications, a standardized approach has been created including technical aspects, pre-assessment and primary scan planes, contrast-enhanced ultrasound (CEUS) procedure, interpretation and reporting. In a previous publication (part 1) the UEAs, imaging methods, preparation of the patients and assessment of global and regional LV function with UEAs were included. The two parts represent a comprehensive state-of-the-art compendium on how to perform CEUS examinations in clinical echocardiography and provide advice on education, qualification and quality control.

Indexed as

cardiomyopathycontrast agentechocardiographymyocardial perfusionthrombustumorultrasoundultrasound enhancing agent

Identifiers

PMID41008743
PMCPMC12468525

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.