Evidence map›Paper›PMID 41008592›Full record

ArticleBiomolecules2025

Synthesis and Bioevaluation of Chalcones as Broad-Spectrum Antiviral Compounds Against Single-Stranded RNA Viruses.

Lorael K M Kirton, Nasser N Yousef, Griffith D Parks, Otto Phanstiel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Evaluation of the Activity of Amino Chalcone AgainstPharmaceuticals (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lorael K M KirtonCollege of Medicine, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.
Nasser N YousefBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, 6900 Lake Nona Blvd, Orlando, FL 32827, USA.
Griffith D ParksBurnett School of Biomedical Sciences, College of Medicine, University of Central Florida, 6900 Lake Nona Blvd, Orlando, FL 32827, USA.
Otto PhanstielCollege of Medicine, University of Central Florida, 12722 Research Parkway, Orlando, FL 32826, USA.ORCID 0000-0001-7101-1311

Funding

Acquisition of timsTOF Pro for Complex Lipidomic AnalysesS10OD030250 · OD · UNIVERSITY OF FLORIDA · PI BASSO, KARI B · 2022 to 2022
$658k
Acquisition of a Q Exactive HF Hybrid Quadrupole-OrbitrapS10OD021758 · OD · UNIVERSITY OF FLORIDA · PI BASSO, KARI B · 2017 to 2017
$600k
Leo Zou MDPI voucherNIH HHS S10 OD021758NIH HHS S10 OD030250University of Central Florida DN12685
6 · The paper itself

Abstract

Chalcones are flavonoid compounds containing an α,β-unsaturated ketone core that are often found in plants and have diverse biological activities including antiviral activity. For example, chalcone

Indexed as

Antiviral AgentsChalconesRNA VirusesChlorocebus aethiopsHumansVero CellsVirus ReplicationAntiviral AgentsChalconeschalconescoronavirusHs27 cellsLa CrossePIV5RNA virusesZika

Identifiers

PMID41008592
PMCPMC12467382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.