Evidence map›Paper›PMID 41007923›Full record

ArticleAnimals : an open access journal from MDPI2025

Thermal Stress Response Profiling Reveals Adaptive Advantages of Indigenous Hercegovačka and Dubska Pramenka Sheep.

Husein Ohran, Naris Pojskic, Jasmin Ramic, Szilvia Kusza, Naida Lojo-Kadric, Aida Hodzic

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Husein OhranDepartment of Basic Veterinary Sciences, University of Sarajevo-Veterinary Faculty, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-2132-4210
Naris PojskicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0001-6765-2976
Jasmin RamicInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0001-6673-1584
Szilvia KuszaCentre for Agricultural Genomics and Biotechnology, Faculty of Agricultural and Food Sciences and Environmental Management, University of Debrecen, Egyetem tér 1, 4032 Debrecen, Hungary.
Naida Lojo-KadricInstitute for Genetic Engineering and Biotechnology, University of Sarajevo, Zmaja od Bosne 8, 71000 Sarajevo, Bosnia and Herzegovina.ORCID 0000-0002-0534-1336
Aida HodzicDepartment of Basic Veterinary Sciences, University of Sarajevo-Veterinary Faculty, Zmaja od Bosne 90, 71000 Sarajevo, Bosnia and Herzegovina.

Funding

Ministry of Education, Science and Youth of Canton Sarajevo, Bosnia and Herzegovina 11/05-14-27884-1/19
6 · The paper itself

Abstract

Climate change poses an increasing challenge to livestock production, making the identification of thermally resilient breeds crucial. This study investigated the expression patterns of eight thermal stress-related genes (HSP90AA1, HSPA8, HSPA1A, IL-6, IL-10, TNF-α, NOS-3, and SOD-2) in two strains of indigenous Pramenka sheep (Hercegovačka and Dubska) under different climatic conditions. Blood samples were collected from 96 sheep across four locations during summer and winter seasons. Gene expression was analyzed using RT-PCR and evaluated against comprehensive environmental data, including the temperature-humidity index (THI). Principal component analysis revealed distinct gene expression patterns between strains and seasons. The Hercegovačka strain showed consistently higher expression of HSP90AA1 compared to the Dubska strain in both seasons (summer: 5.81 vs. 2.47; winter: 4.38 vs. 1.19,

Indexed as

climate resiliencegene expressionheat shock proteinsindigenous sheep breedsthermal adaptation

Identifiers

PMID41007923
PMCPMC12466459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.