Evidence map›Paper›PMID 41007538›Full record

ArticleInternational journal of environmental research and public health2025

Chronic Pain Prevalence and Psychosocial Burden in the Italian Population from the 2019 European Health Interview Survey.

Alice Maraschini, Michael Tenti, William Raffaeli, Laura Iannucci, Lidia Gargiulo, Alessandra Burgio, Giada Minelli, Corrado Fagnani, Emanuela Medda, Maurizio Ferri and 2 more

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alice MaraschiniIstituto Superiore di Sanità, Statistical Service, 00161 Rome, Italy.ORCID 0000-0003-4754-5385
Michael TentiFondazione ISAL, Institute for Research on Pain, 47921 Rimini, Italy.ORCID 0000-0002-4654-018X
William RaffaeliFondazione ISAL, Institute for Research on Pain, 47921 Rimini, Italy.
Laura IannucciISTAT-National Institute of Statistics, 00184 Rome, Italy.ORCID 0009-0000-7788-5386
Lidia GargiuloISTAT-National Institute of Statistics, 00184 Rome, Italy.ORCID 0000-0002-8649-9839
Alessandra BurgioISTAT-National Institute of Statistics, 00184 Rome, Italy.ORCID 0000-0001-8017-7452
Giada MinelliIstituto Superiore di Sanità, Statistical Service, 00161 Rome, Italy.ORCID 0000-0002-2752-9989
Corrado FagnaniIstituto Superiore di Sanità, Centre for Behavioural Sciences and Mental Health, 00161 Rome, Italy.ORCID 0000-0001-5771-7772
Emanuela MeddaIstituto Superiore di Sanità, Centre for Behavioural Sciences and Mental Health, 00161 Rome, Italy.ORCID 0000-0003-4837-4549
Maurizio FerriIstituto Superiore di Sanità, Centre for Behavioural Sciences and Mental Health, 00161 Rome, Italy.
Miriam SalemiIstituto Superiore di Sanità, Centre for Behavioural Sciences and Mental Health, 00161 Rome, Italy.ORCID 0000-0002-0212-5515
Virgilia ToccaceliIstituto Superiore di Sanità, Centre for Behavioural Sciences and Mental Health, 00161 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic pain (CP) is a global healthcare concern requiring careful monitoring. In Italy, the most recent CP prevalence estimates date back to 2003. In this work, we analyzed data from the 2019 European Health Interview Survey, based on a representative sample of the Italian population (n = 44,492), to update national CP prevalence estimates and evaluate its psychosocial burden. CP was detected using a validated questionnaire. Our results show that approximately 10.5 million adults (24.1%) suffer from CP; prevalence and intensity are higher among females and increase with age. In 54.3% of cases, CP was triggered by a diagnosed disease, while 13.6% remain undiagnosed and 14.8% do not seek treatment for CP. Severe CP accounts for 29.4% of cases. Individuals with severe CP are significantly more likely to experience difficulties in social participation (OR 4.82; CI 4.41-5.27), increased work absences (OR 4.18; CI 3.53-4.94), depression (OR 7.10; CI 6.22-8.11), and greater use of primary (OR 2.90; CI 2.64-3.18) and specialist healthcare (OR 2.63; CI 2.40-2.89) as well as diagnostic procedures (OR 2.27; CI 2.07-2.49). Among subjects diagnosed with depression or severe chronic anxiety, CP seems to reduce access to mental health care (OR 0.75; CI 0.61-0.92) and increase abandonment due to financial barriers (OR 1.57; CI 1.07-2.31). Unlike a few countries (e.g., Spain and Denmark) that have recorded a generally increasing trend in CP prevalence, our figures confirm a quite stable national epidemiological pattern. Our estimates underscore the need for careful management of CP and its psychosocial burden. Since data were collected just before the COVID-19 pandemic, they may represent a crucial baseline for monitoring post-pandemic trends.

Indexed as

Chronic PainCost of IllnessAdolescentAdultAgedAged, 80 and overCOVID-19FemaleHealth SurveysHumansItalyMaleMiddle AgedPrevalenceYoung Adultactivity limitationsanxietychronic paindepressionepidemiologyEuropean Health Interview Surveyhealth disparitiesItalyprevalencepsychosocial burdensocial participationtreatment accesswork

Identifiers

PMID41007538
PMCPMC12469650

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.