Evidence map›Paper›PMID 41007481›Full record

ArticleInternational journal of environmental research and public health2025

The Long-Term Impact of Fuel Exposure (LIFE) Study: A Tri-Service Cohort of United States Veterans with Military Occupational Exposure to Jet Fuels.

Elizabeth R Heitz, Nicholas A Tilton, Justin G Bergeron, Gregory Wolff, Jennifer A Rusiecki, Aaron I Schneiderman, Warren S Monks, Christopher Edwards, Gillon D Marchetti, Terra D Vincent-Hall

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of environmental research and public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elizabeth R HeitzExposure Science Program, Health Outcomes Military Exposures, Veterans Health Administration, Department of Veterans Affairs, Washington, DC 20420, USA.ORCID 0009-0007-6996-5475
Nicholas A TiltonExposure Science Program, Health Outcomes Military Exposures, Veterans Health Administration, Department of Veterans Affairs, Washington, DC 20420, USA.ORCID 0000-0003-2312-4076
Justin G BergeronExposure Science Program, Health Outcomes Military Exposures, Veterans Health Administration, Department of Veterans Affairs, Washington, DC 20420, USA.ORCID 0009-0009-2665-8277
Gregory WolffEpidemiology Consult Service, US Air Force School of Aerospace Medicine, Wright-Patterson AFB, Dayton, OH 45433, USA.ORCID 0009-0004-9511-2423
Jennifer A RusieckiDepartment of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.
Aaron I SchneidermanEpidemiology Program, Health Outcomes Military Exposures, Veterans Health Administration, Department of Veterans Affairs, Washington, DC 20420, USA.ORCID 0000-0002-5596-5040
Warren S MonksDirectorate of Clinical Public Health and Epidemiology, Defense Centers for Public Health-Aberdeen, Aberdeen Proving Ground, Aberdeen, MD 21010, USA.
Christopher Edwards711th Human Performance Wing, US Air Force School of Aerospace Medicine, Wright-Patterson AFB, Dayton, OH 45433, USA.
Gillon D MarchettiMilitary Exposure Team, Compensation Service, Veterans Benefits Administration, Department of Veterans Affairs, Washington, DC 20420, USA.ORCID 0009-0004-3195-9780
Terra D Vincent-HallExposure Science Program, Health Outcomes Military Exposures, Veterans Health Administration, Department of Veterans Affairs, Washington, DC 20420, USA.ORCID 0009-0000-4218-4010

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Jet fuels are a complex mixture of hydrocarbons and performance additives, including some compounds with established human toxicity. They represent a significant occupational hazard for military personnel; however, little is known about possible long-term health effects, particularly following cessation of exposure. In response to United States (US) Veterans' concerns, the US Department of Veterans Affairs (VA) and the Department of Defense (DoD) launched a large retrospective cohort study to assess the impact of military occupational jet fuel exposure on Veterans' health. The Long-Term Impact of Fuel Exposure (LIFE) cohort consists of over 1.3 million Veterans who entered service on or after 1 January 1995, including both individuals with jet fuel-exposed occupations in their service history and a random sample of unexposed Veterans. Data from multiple VA and DoD administrative datasets were linked to evaluate morbidity, disability, and mortality endpoints. Analyses are underway to assess associations between jet fuel exposure and adverse health outcomes in multiple body systems. This study represents the largest effort to date to investigate these effects, with the intention of informing policies affecting Veterans for years to come.

Indexed as

Databases, FactualHydrocarbonsMilitary PersonnelOccupational ExposureVeteransAdultAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedPersons with DisabilitiesUnited StatesYoung AdultHydrocarbonsaircraft fuelchronic diseaseexposure assessmenthealth outcomesjet fuellong-term effectsmilitaryoccupational healthretrospective cohortVeterans

Identifiers

PMID41007481
PMCPMC12470227

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.