Evidence map›Paper›PMID 41007407›Full record

ArticleBiology2025

Expression Dynamics of Neurotransmitter System Genes in Early Sea Urchin Embryos: Insights from a Four-Species Comparative Transcriptome Analysis.

Yuri B Shmukler, Nina M Alyoshina, Yulia O Nikishina, Denis A Nikishin

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuri B ShmuklerKoltzov Institute of Developmental Biology RAS, Vavilov Street, 26, Moscow 119334, Russia.ORCID 0000-0002-1825-1081
Nina M AlyoshinaKoltzov Institute of Developmental Biology RAS, Vavilov Street, 26, Moscow 119334, Russia.ORCID 0000-0002-2252-2737
Yulia O NikishinaKoltzov Institute of Developmental Biology RAS, Vavilov Street, 26, Moscow 119334, Russia.ORCID 0009-0000-2044-6155
Denis A NikishinKoltzov Institute of Developmental Biology RAS, Vavilov Street, 26, Moscow 119334, Russia.ORCID 0000-0002-9238-9206

Funding

Government Program for Basic Research № 0088-2024-0012
6 · The paper itself

Abstract

Transmitters such as serotonin, dopamine, noradrenaline, and acetylcholine act as regulators or triggers of numerous processes in the early embryo, including in sea urchins. However, the identity of these mechanisms relative to mature nervous systems remains controversial. The aim of this study was to comprehensively characterize the transcriptomic basis of these as well as glutamatergic, GABAergic and histaminergic systems by comparing publicly available RNA-Seq data across four sea urchin species

Indexed as

acetylcholinecomparative transcriptomicsdopamineearly developmentglutamateinterspecies variabilityneurotransmitter systemssea urchinserotonintranscriptome

Identifiers

PMID41007407
PMCPMC12467107

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.