Evidence map›Paper›PMID 41007389›Full record

ArticleBiology2025

Comparative Study of Leech-Derived Tryptase Inhibitor Genes in Four Medicinal Leech Species.

Mingkang Xiao, Fang Zhao, Tianyu Ye, Rui Ai, Lizhou Tang, Zichao Liu, Qingqian Zeng, Zuhao Huang, Gonghua Lin

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mingkang XiaoKey Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, School of Life Sciences, Jinggangshan University, Ji'an 343009, China.ORCID 0009-0006-2518-0003
Fang ZhaoKey Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, School of Life Sciences, Jinggangshan University, Ji'an 343009, China.ORCID 0009-0004-7778-8892
Tianyu YeKey Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, School of Life Sciences, Jinggangshan University, Ji'an 343009, China.ORCID 0009-0005-4182-3737
Rui AiKey Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, School of Life Sciences, Jinggangshan University, Ji'an 343009, China.
Lizhou TangCollege of Life Sciences, Jiangxi Normal University, Nanchang 330022, China.
Zichao LiuSchool of Agronomy and Life Sciences, Kunming University, Kunming 650214, China.ORCID 0000-0002-7509-6209
Qingqian ZengGuangdong Institute of Traditional Chinese Medicine, Guangzhou 510630, China.
Zuhao HuangKey Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, School of Life Sciences, Jinggangshan University, Ji'an 343009, China.
Gonghua LinKey Laboratory of Jiangxi Province for Biological Invasion and Biosecurity, School of Life Sciences, Jinggangshan University, Ji'an 343009, China.

Funding

Double Thousand Plan of Jiangxi Province No. jxsq2023201063Foundation of Yunnan International Joint Laboratory with South and Southeast Asia for the Inte-grated Development of Animal-derived Anti-thrombosis Chinese Medicine No. 202503AP140025Key Laboratory of Jiangxi Province for Biological Invasion and Biosecurity No. 2023SSY02111National Natural Science Foundation of China No. 82260742
6 · The paper itself

Abstract

Leeches are aquatic annelids of significant medicinal value, known to produce a variety of antithrombotic proteins. However, the extent of interspecies variation in these bioactive components remains poorly understood. In this study, next-generation sequencing and the

Indexed as

anticoagulant activityantithrombotic geneeukaryotic expressiongenetic variationmedicinal leeches

Identifiers

PMID41007389
PMCPMC12467411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.