Evidence map›Paper›PMID 41007361›Full record

ArticleBiology2025

Transcriptome Analysis of Muscle Tissue from Three Anatomical Locations in Male and Female Kazakh Horses.

Ayixie Wubuli, Yi Su, Xinkui Yao, Jun Meng, Jianwen Wang, Yaqi Zeng, Linling Li, Wanlu Ren

Abstract read
In one paragraph

Article in Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ayixie WubuliCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Yi SuCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0009-0009-8046-9442
Xinkui YaoCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Jun MengCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0009-0004-4211-0870
Jianwen WangCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0000-0001-7148-4557
Yaqi ZengCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0009-0000-1881-1221
Linling LiCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.
Wanlu RenCollege of Animal Science, Xinjiang Agricultural University, Urumqi 830052, China.ORCID 0009-0003-5822-8366

Funding

the 2025 Central Guidance for Local Science and Technology Development Funding Project "Research on Breeding and Exercise Performance Regulation Mechanisms in Horses" ZYYD2025JD02the Major Science and Technology Special Project of the Xinjiang Uygur Autonomous Region 2022A02013-1
6 · The paper itself

Abstract

The Kazakh horse, a versatile breed, is renowned for stable genetic performance and strong tolerance to coarse feed. Sex is a key factor influencing skeletal muscle development. However, the mechanisms underlying sex-specific regulation of equine muscle growth remain obscure. This study employed transcriptomic analysis to investigate sex-associated molecular differences in skeletal muscle of Kazakh horses. The experimental cohort comprised four three-year-old Kazakh stallions and four three-year-old Kazakh mares. After slaughter, six groups of muscle samples were collected immediately, including the longissimus dorsi, rectus abdominis, and diaphragm muscles of both sexes, with four biological replicates per group. RNA-seq analysis revealed 361, 230, and 236 differentially expressed genes (DEGs) in the longissimus dorsi of stallion Kazakh horses (Mb) vs. the longissimus dorsi of mare Kazakh horses (Gb), the rectus abdominis of stallion Kazakh horses (Mf) vs. the rectus abdominis of mare Kazakh horses (Gf), and the diaphragm of stallion Kazakh horses (Mg) vs. the diaphragm of mare Kazakh horses (Gg), respectively. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses indicated that DEGs such as

Indexed as

differentially expressed geneKazakh horseRNA-seqskeletal muscle

Identifiers

PMID41007361
PMCPMC12467203

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.