Evidence map›Paper›PMID 41007193›Full record

ReviewBioengineering (Basel, Switzerland)2025

Applications of Adipose Tissue Micrografts (ATM) and Dermis Micrografts (DMG) in Wound Healing: A Scoping Review of Clinical Studies.

Konstantinos Zapsalis, Orestis Ioannidis, Elissavet Anestiadou, Maria Pantelidou, Konstantinos Siozos, Christos Xylas, Georgios Gemousakakis, Angeliki Cheva, Chryssa Bekiari, Antonia Loukousia and 6 more

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Konstantinos Zapsalis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Orestis Ioannidis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.ORCID 0000-0002-0861-8783
Elissavet Anestiadou4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.ORCID 0000-0001-5650-7319
Maria PantelidouDepartment of Plastic and Reconstructive Surgery, James Paget University Hospitals NHS Foundation Trust, Gorleston, Great Yarmouth NR31 6LA, Norfolk, UK.
Konstantinos Siozos4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.ORCID 0009-0004-1901-3909
Christos Xylas4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Georgios Gemousakakis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Angeliki ChevaPathology Department, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0002-5374-1772
Chryssa BekiariExperimental and Research Center, Papageorgiou General Hospital of Thessaloniki, 56403 Thessaloniki, Greece.
Antonia LoukousiaPathology Department, Faculty of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.ORCID 0000-0003-3991-0645
Savvas Symeonidis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Stefanos Bitsianis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.ORCID 0000-0001-8281-1189
Manousos-Georgios Pramateftakis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Efstathios Kotidis4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Ioannis Mantzoros4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.
Stamatios Angelopoulos4th Department of Surgery, General Hospital "George Papanikolaou", Aristotle University of Thessaloniki, 57010 Exochi, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adipose tissue micrografts (ATM) and dermis micrografts (DMG) have emerged as promising autologous therapies in regenerative wound care, leveraging mechanically disaggregated cell-matrix constructs to modulate the wound microenvironment and promote tissue repair. This scoping review systematically analyzed clinical studies investigating ATMs and DMGs in acute and chronic wounds. Eight studies, comprising randomized controlled trials, observational studies, and case series, were identified, involving diverse wound types such as burns, ulcers, surgical dehiscence, and posttraumatic defects. All interventions utilized mechanical disaggregation (Rigenera

Indexed as

adipose tissue micrograftsautologous graftsdermis micrograftsregenerative medicineRigenera systemstromal vascular fractiontissue regenerationwound healing

Identifiers

PMID41007193
PMCPMC12467152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.