ArticleBioengineering (Basel, Switzerland)2025
The Influence of a Predegenerated Autological Nerve Graft on the Results of Peripheral Nerve Repair in the Upper Extremities After Injuries.
Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Functional and Morphological Outcomes of Duration-Dependent Electrical Stimulation in Silicone Conduit-Mediated Peripheral Nerve Repair in Rats.Bioengineering (Basel, Switzerland) · 2026Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The improvement in peripheral nerve repair is still challenging, with the process being difficult and frequently unsatisfying. Injuries, even minor ones, can lead to limitations, including the loss of important life functions such as fingers, hands, or all limbs. Our previous research on animals revealed that the distal part of autologous predegenerated nerve grafts, which were injured and left in place for 7 days, was more capable of supporting reconstructed nerve regeneration. Little is known about the efficacy of using predegenerated autologous grafts in humans. Encouraged by promising results in animal models, we decided to investigate this process in humans. A total of 31 patients were evaluated in the study; 19 predegenerated (injured and left in situ for 7 days) autologous sural nerve implants and 12 fresh sural nerve implants were used, and the period of 2 years after operation was chosen as the time of final clinical assessment. Clinical assessment and motor and sensory nerve conduction velocity were assessed. All data were statistically analyzed using stepwise regression testing and a one-way analysis of variance followed by Tukey's test for continuous values and the Mann-Whitney U test for ordinal values. Differences were considered statistically significant for
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