Optimization and Analysis of Tangential Component Orientations in OPM-MEG Sensor Array.

Wenli Wang, Fuzhi Cao, Nan An, Wen Li, Chunhui Wang, Zhenfeng Gao, Min Xiang, Xiaolin Ning

Abstract read

In one paragraph

Article in Bioengineering (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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5 · Who and what money

Authors and funding

8 authors.

Wenli WangKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.

Fuzhi CaoKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.ORCID 0000-0002-0510-2757

Nan AnHangzhou Institute of National Extremely-Weak Magnetic Field Infrastructure, 465 Binan Rd., Binjiang District, Hangzhou 310051, China.

Wen LiKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.

Chunhui WangKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.

Zhenfeng GaoKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.

Min XiangKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.ORCID 0000-0002-0239-3392

Xiaolin NingKey Laboratory of Ultra-Weak Magnetic Field Measurement Technology, Ministry of Education, School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing 100191, China.ORCID 0000-0003-3563-3601

Funding

China Postdoctoral Science Foundation 2023M730179, 2024M754067, GZC20233379Industrial Technology Basic Public Service Platform Project 2022-189-18Key Laboratory of Weak Magnetic Detection Technology, Ministry of Education, Innovation Program for Quantum Science and Technology 2021ZD0300503Key Research and Development Program of Shandong Province 2022ZLGX03Major Basic Research of Shandong Provincial Natural Science Foundation ZR2023ZD14National Natural Science Foundation of China 62401028Natural Science Foundation of Shandong Province ZR2021MH236Postdoctoral Fellowship Program and China Postdoctoral Science Foundation BX20240456, BX20240463

6 · The paper itself

Abstract

Optically pumped magnetometers (OPMs) have brought a transformative advancement to magnetoencephalography (MEG), enabling flexible, noncryogenic, and wearable neuroimaging systems. In particular, the development of triaxial OPM sensors allows for simultaneous measurement of full magnetic field vectors, including both radial and additional tangential components. Previous studies have shown that incorporating tangential components helps enhance the separation between neural signals and external interference, but their optimal configurations remain unclear. This study systematically investigated the impact of tangential component configurations on array sensitivity and the lead field correlation coefficient (R12) in triaxial OPM-MEG sensor arrays, considering tangential component rotations, relative orientations of sensor and source, source depths, and head model types. Based on the above analysis, we proposed an optimization strategy aimed at minimizing R12, referred to as R12-minimization array optimization (RMAO), to explore the optimal configuration of tangential components. The simulation results showed that the proposed method significantly enhanced sensitivity to cortical sources and effectively suppressed external interference, enabling more accurate source localization. This study highlights the critical role of tangential components in improving system performance and provides theoretical foundation and methodological guidance for the design of triaxial OPM-MEG sensor arrays.

Indexed as

array sensitivitylead field correlation coefficientsmagnetoencephalographyOPM-MEGsource localizationtangential component

Identifiers

PMID41007148

DOI10.3390/bioengineering12090903

PMCPMC12467417

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.