Evidence map›Paper›PMID 41007135›Full record

ReviewChildren (Basel, Switzerland)2025

The Epidemiology of Nontuberculous Mycobacteria in Cystic Fibrosis.

Aikaterini Sotiropoulou, Ioanna Loukou, Christiana Vliora, Konstantinos Douros, Maria Moustaki

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aikaterini SotiropoulouCystic Fibrosis Department, "Agia Sofia" Children's Hospital, 11527 Athens, Greece.
Ioanna LoukouCystic Fibrosis Department, "Agia Sofia" Children's Hospital, 11527 Athens, Greece.
Christiana Vliora1st Health Authority of Attica, 11521 Athens, Greece.
Konstantinos DourosPediatric Allergy and Respiratory Unit, 3rd Department of Pediatrics, "Attikon" University Hospital, School of Medicine, National and Kapodistrian University of Athens, 12462 Athens, Greece.ORCID 0000-0001-7632-1159
Maria MoustakiCystic Fibrosis Department, "Agia Sofia" Children's Hospital, 11527 Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNontuberculous mycobacteria (NTM) are opportunistic pathogens responsible for chronic pulmonary infections, primarily affecting individuals with underlying conditions such as cystic fibrosis (CF). The aim of this review is to present the epidemiological profile of NTM in CF patients, with a focus on incidence, prevalence, predominant species, and geographic distribution.

methodsThe search included cross-sectional, retrospective, and prospective observational studies published in English that reported epidemiological data concerning the isolation and/or infection of individuals with CF by NTM. NTM infection was defined as the isolation of any NTM species at least once per patient. Out of an initial 1120 references identified in PubMed, and following the application of exclusion criteria based on PRISMA guidelines, a total of 78 studies were included.

resultsThe reported prevalence of NTM in CF patients ranges globally from 0% to 40.9%. This wide variability is attributed to population heterogeneity, study period, and geographical region. Of the studies included, 30 were conducted in Europe and 25 in the U.S.A.

conclusionsNontuberculous mycobacteria are significant pathogens in patients with cystic fibrosis, with a negative impact on respiratory health.

Indexed as

cystic fibrosisepidemiologyM. abscessusM. intracellularenontuberculous mycobacteria

Identifiers

PMID41007135
PMCPMC12468492

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.