Evidence map›Paper›PMID 41007067›Full record

ReviewChildren (Basel, Switzerland)2025

Clinical Impact of Patient-Specific 3D Models in Neonatal Surgery: A Case-Based Review of Applications and Future Directions.

Oscar Girón-Vallejo, Bernardo Garcia-Nuñez, Isidoro Narbona-Arias, Alexander Siles-Hinojosa, Francisco Javier Murcia-Pascual, Moutasem Azzubi, Ignacio Gorriti, Dario Garcia-Calderon, Antonio Piñero-Madrona, Lucas Krauel

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Oscar Girón-VallejoVirgen de la Arrixaca Children's Hospital, El Palmar, 30120 Murcia, Spain.ORCID 0000-0002-3229-6219
Bernardo Garcia-NuñezCorporació Sanitaria Parc Taulí, 08208 Barcelona, Spain.ORCID 0000-0001-7790-2166
Isidoro Narbona-AriasRegional University Hospital, 29010 Málaga, Spain.ORCID 0000-0001-9148-9881
Alexander Siles-HinojosaRegional University Hospital, 29010 Málaga, Spain.ORCID 0000-0001-7045-4284
Francisco Javier Murcia-PascualReina Sofía University Hospital, 14004 Córdoba, Spain.
Moutasem AzzubiKing Abdullah Specialized Chidren's Hospital, Riyadh 14611, Saudi Arabia.
Ignacio GorritiDepartment of Natural Sciences, Universidad Nacional de Rio Negro, Viedma R8500, Argentina.
Dario Garcia-CalderonVirgen de la Arrixaca Children's Hospital, El Palmar, 30120 Murcia, Spain.
Antonio Piñero-MadronaVirgen de la Arrixaca Children's Hospital, El Palmar, 30120 Murcia, Spain.ORCID 0000-0002-7718-8318
Lucas KrauelPediatric Surgery and 3D4H Unit, SJD Barcelona Children's Hospital, Universitat de Barcelona, 08950 Barcelona, Spain.ORCID 0000-0002-0254-4488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D) modeling and printing technologies are increasingly used in pediatric surgery, offering improved anatomical visualization, surgical planning, and personalized approaches to complex conditions. Compared to standard imaging, patient-specific 3D models-virtual or printed-provide a more intuitive spatial understanding of congenital anomalies, tumors, and vascular anomalies. This review compiles evidence from pediatric surgical fields including oncology, abdominal, and thoracic surgery, highlighting the clinical relevance of 3D applications. The technological workflow-from image segmentation to computer-aided design (CAD) modeling and multimaterial printing-is described, emphasizing accuracy, reproducibility, and integration into hospital systems. Several clinical cases are presented: neuroblastoma, cloacal malformation, conjoined twins, and two cases of congenital diaphragmatic hernia (one with congenital pulmonary airway malformation, CPAM). In each, 3D modeling enhanced anatomical clarity, increased surgeon confidence, and supported safer intraoperative decision-making. Models also improved communication with families and enabled effective multidisciplinary planning. Despite these advantages, challenges remain, such as production time, cost variability, and lack of standardization. Future directions include artificial intelligence-based automation, expanded use of virtual and mixed reality, and prospective validation studies in pediatric cohorts. Overall, 3D modeling represents a significant advance in pediatric precision surgery, with growing evidence supporting its safety, clinical utility, and educational value.

Indexed as

3D modelingcongenital malformationsmedical imagingneonatal surgeryoncologypatient-specific modelssurgical planning

Identifiers

PMID41007067
PMCPMC12469229

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.