Evidence map›Paper›PMID 41006754›Full record

ArticleScientific reports2025

Numerical modeling and simulation of stochastic fractional order model for COVID-19 infection in Mittag-Leffler kernel.

Muhammad Altaf Khan, Zain Ul Abadin Zafar, Irfan Ahmad, Nurulfiza Mat Isa, Ebraheem Alzahrani

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Muhammad Altaf Khan *Department of Mathematics, Saveetha School of Engineering, SIMATS, Saveetha University, 602105, Chennai, Tamil Nadu, India. altafdir@gmail.com.
Zain Ul Abadin Zafar *Department of Mathematics, Faculty of Science and Technology, University of Central Punjab, Lahore, Pakistan.
Irfan Ahmad *Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.
Nurulfiza Mat Isa *Laboratory of Vaccine and Biomolecules, Institute of Bioscience, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia.
Ebraheem Alzahrani *Department of Mathematics, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, we develop and analyze a fractional-order stochastic model for COVID-19 transmission, incorporating the effects of vaccination. The model is formulated using the Atangana-Baleanu fractional derivative in the Caputo sense, which captures memory and hereditary properties of disease transmission more accurately than classical derivatives. We first examine the positivity and boundedness of the deterministic fractional model and determine its equilibrium points. The model is then extended to a fractional stochastic differential equation (FSDE) to account for random fluctuations and uncertainties in disease dynamics. We establish the existence and uniqueness of solutions for the FSDE model using stochastic analysis techniques. To numerically solve the FSDE, we develop a novel numerical scheme that accommodates the non-local nature of the Atangana-Baleanu derivative. The real data of COVID-19 in Pakistan have been used to estimate the model parameters. Numerical simulations are presented for both the deterministic fractional model and its stochastic counterpart. These simulations illustrate the impact of the fractional-order parameter on disease dynamics, showing how different orders influence the rate of infection and convergence to equilibrium. Additionally, we analyze scenarios under varying parameter values to explore conditions for disease elimination, highlighting the role of vaccination and stochasticity. Our findings demonstrate that fractional stochastic modeling provides deeper understanding of COVID-19 transmission dynamics and can be a valuable tool in assessing control strategies under uncertainty. The originality of this work stems from the integration of Atangana-Baleanu fractional derivatives with stochastic modeling, supported by a new numerical solution method providing a more realistic and flexible approach to modeling COVID-19 transmission under uncertainty.

Indexed as

COVID-19Computer SimulationHumansPakistanSARS-CoV-2Stochastic ProcessesVaccination

Identifiers

PMID41006754
PMCPMC12475229

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