ArticleScientific reports2025
Genome analysis of viral hemorrhagic septicemia virus isolated from Paralichthys olivaceus in China.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
This study determined the complete genomic sequence of the viral hemorrhagic septicemia virus (VHSV) strain GY-2307 isolated form farmed paralichthys olivaceus in northeast China. The whole genome length of GY-2307 comprised 11,140 nucleotides (nt), and the overall organization was typical of that observed for all other VHSV strains. The phylogenetic analysis results indicated that the GY-2307 isolate belonged to genotype Ⅳa and significantly related to other Korean and Japanese isolates. The N, P, M, NV and L genes of GY-2307 were compared with the VHSV sequences in GenBank. The results revealed that 315 nt were substituted, 71 of which exhibited amino acid change in the GY-2307 genome. In the G gene, specific nucleotides and amino acid variations of the Chinese isolates of VHSV were observed when compared with 28 isolates from other counties. Of the 23 nucleotide sites that changed, 9 resulted in amino acid substitution. The data further indicated that the genotype Ⅳa VHSV was introduced to and evolved in paralichthys olivaceus farm environments in China.
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