Evidence map›Paper›PMID 41006460›Full record

ArticleScientific reports2025

Screening of advanced fibrosis and metabolic dysfunction-associated steatotic liver disease using transient elastography in vulnerable population.

Robert Nastasa, Carol Stanciu, Ermina Stratina, Sebastian Zenovia, Remus Stafie, Adrian Rotaru, Catalin Sfarti, Irina Girleanu, Horia Minea, Ana-Maria Singeap and 2 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The SCANVIRViruses · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Robert NastasaDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Carol StanciuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Ermina StratinaDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania. stratina.ermina@yahoo.com.
Sebastian ZenoviaDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Remus StafieDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Adrian RotaruDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Catalin SfartiDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Irina GirleanuDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Horia MineaDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Ana-Maria SingeapDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Laura HuibanDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.
Anca TrifanDepartment of Gastroenterology, Grigore T. Popa University of Medicine and Pharmacy, Iasi, 70015, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liver cirrhosis is the primary contributor to global mortality associated with chronic liver diseases (CLD). Certain liver infections, including viral hepatitis B (VHB) and C (VHC), alcohol-related liver disease (ALD), and metabolic dysfunction-associated steatotic liver disease (MASLD) are significant contributors to the development of liver cirrhosis. This study aimed to evaluate the prevalence of liver steatosis and fibrosis in individuals with vulnerable conditions. Subjects residing in a rural Romanian county or having lower educational attainment were selected for this study. Following the acquisition of informed consent, a demographic, clinical, and physiological characterization was conducted for each participant. The AUDIT-C questionnaire was obtained from every participant. Transient Elastography (TE) measured liver fibrosis, while blood tests screened for the presence of hepatitis viruses B and C. Among the 571 screened vulnerable subjects, 52.7% were males, and 17.3% were identified as heavy drinkers. Metabolic syndrome was identified in 37.3% of patients and 70% of subjects exhibited a body mass index of ≥ 25 kg/m

Indexed as

Elasticity Imaging TechniquesFatty LiverLiver CirrhosisMetabolic SyndromeAdultAgedFemaleHumansMaleMass ScreeningMiddle AgedPrevalenceRisk FactorsRomaniaAlcohol-related liver diseaseChronic viral hepatitisLiver fibrosisMetabolic dysfunction-associated steatotic liver diseaseTransient elastographyVulnerable population

Identifiers

PMID41006460
PMCPMC12475056

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.