Evidence map›Paper›PMID 41006405›Full record

Observational studyScientific reports2025

Adverse effects and SARS-CoV-2 infection after COVID-19 vaccination among the vaccinated people of Bangabandhu Sheikh Mujib Medical University Hospital in Dhaka, Bangladesh: a pilot study.

Elora Sharmin, Khadija Majumder, Sheikh Foyez Ahmed

Abstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elora SharminDepartment of Pharmacology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. sheikh.foyez@yahoo.com.
Khadija MajumderSummerview Medical Clinic (Family Medicine and Wellness Clinic), Newmarket, Canada.
Sheikh Foyez AhmedDepartment of Cardiology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. sheikh.foyez@yahoo.com.

Funding

BSMMU 2021-2022/02
6 · The paper itself

Abstract

The Pfizer, Moderna, AstraZeneca, and Sinopharm COVID-19 vaccines have demonstrated robust safety and efficacy in Phase II clinical trials. We aimed to assess adverse effects and post-vaccination infection rates amongst vaccinated people at Bangabandhu Sheikh Mujib Medical University (BSMMU). In this prospective observational follow-up pilot study, 2534 subjects aged below 20 years or older who had received two doses of the Pfizer, Moderna, AstraZeneca, and Sinopharm COVID-19 vaccines were selected using a consecutive sampling method from June to November 2021. We evaluated the local and systemic side effects of the subjects. The subjects under study were followed up within seven days and up to 28 days after 1st and 2nd dose of all four vaccine. We also assessed post-vaccination infection rates among individuals tested for SARS-CoV-2 via PCR or rapid antigen tests. The demographic variables, type of administered vaccine, adverse effects, and presence of comorbidities were collected. Descriptive statistics (mean, standard deviation) were performed by using SPSS. Among 2534 participants who were vaccinated, systemic side effects were reported by 14.4% (379/2534) after the first dose and 10.4% (265/2534) after the second dose across all vaccines. Among vaccine-specific groups, systemic side effects were observed in 6.6% (109/1635) and 5.2% (85/1635) for the first and second doses of Pfizer; 34.3% (136/396) and 42% (166/396) for Moderna; 6.5% (32/488) and 2.9% (14/488) for Sinopharm; and 13.3% (2/15) for AstraZeneca after both doses. Local side effects were reported in 4.8% (79/1635) and 2% (32/1635) for the first and second doses of Pfizer; 45.5% (82/396) and 26% (106/396) for Moderna; 10.7% (53/488) and 2.6% (13/488) for Sinopharm; and primarily local effects for AstraZeneca. Post-vaccination infection among the vaccinated participants across all vaccines were ranging from 0.1 to 0.3% after the first and second doses.

Indexed as

COVID-19COVID-19 VaccinesSARS-CoV-2VaccinationAdolescentAdultAgedBangladeshFemaleFollow-Up StudiesHospitals, UniversityHumansMaleMiddle AgedPilot ProjectsProspective StudiesCOVID-19 VaccinesAdverse effectAdverse effectsBangladeshBSMMUCOVID-19Covid-19 vaccineInfectionSARS-CoV-2 vaccine

Identifiers

PMID41006405
PMCPMC12475045

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.