Evidence map›Paper›PMID 41006372›Full record

ArticleScientific reports2025

Mechanisms of Saposhnikovia divaricata in attenuating NaAsO

Dan Gu, Xian-Li Chen, Heng-Lin He, Mei Xia, Jin-Ying Huang, Guang-Hui He, Xin-Yu Wang, Yan-Yu Chen, Wen-Run Kang, Bao-Fei Sun and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Dan Gu *Department of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Xian-Li Chen *Department of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Heng-Lin He *Department of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Mei Xia *Department of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Jin-Ying HuangDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Guang-Hui HeDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Xin-Yu WangDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Yan-Yu ChenDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Wen-Run KangDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Bao-Fei SunKey Laboratory of Human Brain Bank for Functions and Diseases of Department of Education of Guizhou Province, Guizhou Medical University, Guiyang, 561113, Guizhou, China.
Xiao-Hong LiuDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China.
Wei ZhouDepartment of Pharmaceutical Analysis, School of Pharmacy, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China. drwzhou@126.com.
Xian-Lu ZhuoAffiliated Hospital of Guizhou Medical University, Guiyang, 550004, Guizhou, China. zhuoxianlu@gmc.edu.cn.
Ji-Gang PanDepartment of Physiology, School of Basic Medical Sciences, Guizhou Medical University, No. 6 Ankang Avenue, Gui'an New District, Guiyang, 561113, Guizhou, China. jgpan@gmc.edu.cn.

Funding

Guizhou Provincial Science and Technology Support Project No. 2021-General 415the College Students' innovation and entrepreneurship training program of Guizhou Province S202210660077the College Students' innovation and entrepreneurship training program of Guizhou Province S202210660078the Department of Education of Guizhou Province Guizhou Teaching and Technology [2023]015the National Natural Science Foundation of China 31960188
6 · The paper itself

Abstract

Saposhnikovia divaricata (S. divaricata) has demonstrated significant efficacy in mitigating arsenic poisoning. However, its protective effects of S. divaricata against NaAsO

Indexed as

ApiaceaeArsenitesDrugs, Chinese HerbalNeuronsNeuroprotective AgentsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSignal TransductionSodium CompoundsAnimalsApoptosisCell SurvivalMiceMolecular Docking SimulationNetwork PharmacologyProtein Interaction MapsArsenitesDrugs, Chinese HerbalNeuroprotective AgentsPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktsodium arseniteSodium CompoundsNerve injuryNetwork pharmacologyPI3K/AKT pathwaySaposhnikovia divaricataSodium arsenite

Identifiers

PMID41006372
PMCPMC12474866

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.