ArticleScientific reports2025
Medicinal potential of Morchella esculenta oil inhibits cancer cell proliferation, metabolite characterization through GCMS, GC×GC-TOF-MS and UHPLC-QTOF-MS.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Exploring Morchella mushrooms: a natural approach to cancer therapy.Archives of microbiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study investigated comprehensive phytochemical profile through high resolution techniques like GCMS, GC×GC-TOF-MS, UHPLC-QTOF-MS, total phenolic content, total flavonoid content, antioxidant, and anticancer activities of Morchella esculenta oil using in vitro approaches. The results showed the identification of 19 (GCMS) 20 (UHPLC-QTOF-MS) and 68 (GC×GC-TOF-MS) phytochemical compounds belonging to diverse classes of compounds. Hexadecenoic acid, oleic acid, palmitic acid, linoleic acid, octanoic acid, C16 sphinganine, allopumiliotoxin267A, 3'-Hydroxy-T2 Toxin were the main compounds identified. The Morchella esculenta oil showed moderate phenolic content (13.26 ± 2.52 mg GAE/g dw), flavonoid content (11.35 ± 1.58 mg RE/g dw) and antioxidant activities (DPPH-IC50 = 118.46 µg/mL; ABTS-IC50 = 125 µg/mL; and FRAP-IC50 = 117.90 µg/mL). Using human cervix (HeLa), human colon (HCT-116) and human breast cancer (MCF-7) cell lines, essential oil of Morchella esculenta showed a dose/time-dependent antiproliferative and cytotoxicity activity with GI50 values of 27.61 µg/mL, 19.52 µg/mL, and 31.34 µg/mL respectively. The obtained results confirmed that Morchella esculenta oil is a rich source of bioactive molecules with strong antiproliferative and cytotoxicity potential towards cancer cell lines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.