Evidence map›Paper›PMID 41006283›Full record

ReviewNPJ science of food2025

Potential health benefits of insect bioactive metabolites and consumer attitudes towards edible insects.

Jackson Ishara, Idaresit Ekaette, Rehema Matendo, Grant Vandenberg, Saliou Niassy, Karume Katcho, John Kinyuru

Registry-linked trialAbstract readReview
In one paragraph

Review in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07456319 (Sustainable Insect-based Protein Supplement in the Elderly), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07456319 nacompletednot on this map

Sustainable Insect-based Protein Supplement in the Elderly: a Pilot Study

TypeinterventionalSponsorUniversitat Oberta de CatalunyaRan2024 to 2024Enrolled30ConditionsAging, Nutrition, Sustainable Diets, Cardiometabolic HealthArmsINSECT - Protein suplement based on edible insect flour, Control
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Antioxidants (Basel, Switzerland) · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jackson IsharaDepartment of Food Science and Technology, Université Evangélique en Afrique, P.O. Box 3323, Bukavu, Democratic Republic of the Congo. jack.ishara@outlook.com.ORCID http://orcid.org/0000-0003-4789-4040
Idaresit EkaetteDepartment of Food Science and Agricultural Chemistry, McGill University, Ste-Anne-de-Bellevue, Quebec, H9X 3V9, Canada.ORCID http://orcid.org/0009-0005-2254-9584
Rehema MatendoDepartment of Food Science and Technology, Université Evangélique en Afrique, P.O. Box 3323, Bukavu, Democratic Republic of the Congo.ORCID http://orcid.org/0000-0002-8492-7166
Grant VandenbergChair of Educational Leadership (CLE) in Primary Production and Processing of Edible Insects (CLEIC), Quebec, Canada.ORCID http://orcid.org/0000-0001-9172-7595
Saliou NiassyInter-African Phytosanitary Council of African Union (AU-IAPSC), P.O Box 4170, Yaoundé, Cameroon.ORCID http://orcid.org/0000-0003-1061-4041
Karume KatchoFaculty of Agriculture and Environmental Sciences, Université Evangélique en Afrique, Bukavu, 3323, Democratic Republic of the Congo.ORCID http://orcid.org/0000-0003-1146-8808
John KinyuruDepartment of Food Science and Technology, Jomo Kenyatta University of Agriculture and Technology, P.O. Box 62000-00200, Nairobi, Kenya.ORCID http://orcid.org/0000-0001-5006-5599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Particular attention has been paid to the nutritional potential of edible insects as well as the health benefits associated with their bioactive compounds. This paper focused on an in-depth review compiling the most recent information on health benefits of insect bioactive metabolites as well as their purification and identification, in addition to consumer attitudes towards edible insects. It was found that, insect bioactive metabolites, including marcocarpal, grandinol, trolline, pancratistatin, narciclasin, ungeremin, cantharidin, cordycepin, roseoflavin, lecithin, reblastatin, chitin, chitosan and desmosterol deemed to have biological activities, such as tumor suppression, anticancer, antihypertensive, anti-inflammatory, antioxidant, immunomodulator, neuroprotective, glycemic and lipid regulation, blood pressure reduction, regulation of intestinal bacterial flora and cardiovascular protection among others. Furthermore, proper sample preparation and extraction is the first step in the purification of bioactive metabolites from edible insects. After concentration, bioactive metabolites are purified using chromatographic and separation techniques including High-Performance Liquid Chromatography (HPLC), Gas Chromatography (GC), Thin-Layer Chromatography (TLC), Size-Exclusion Chromatography (SEC). Finally, their nutritional potential, health benefits, environmentally friendly, great taste, traditions, taboo, safety concerns, unpleasant past experiences, allergies, and unnaturalness are among the main factors influencing attitudes towards insect consumption.

Identifiers

PMID41006283
PMCPMC12475101

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.