Evidence map›Paper›PMID 41006264›Full record

ArticleNPJ breast cancer2025

Breast cancer Intraoperative Margin Assessment using specimen PET-CT (BIMAP).

Anne-Sofie De Crem, Philippe Tummers, Herman Depypere, Geert Braems, Rawand Salihi, Glenn Vergauwen, Giovanni Cisternino, Koen Van de Vijver, Pieter De Visschere, Kathia De Man and 7 more

Abstract read
In one paragraph

Article in NPJ breast cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Anne-Sofie De CremDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium. anne-sofie.de.crem@hotmail.com.
Philippe TummersDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium.
Herman DepypereDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium.
Geert BraemsDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium.
Rawand SalihiDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium.
Glenn VergauwenDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium.
Giovanni CisterninoBreast Surgery Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Koen Van de VijverCancer Research Institute Ghent, Ghent, Belgium.
Pieter De VisschereCancer Research Institute Ghent, Ghent, Belgium.
Kathia De ManDepartment of Diagnostic Sciences, Ghent University, Ghent, Belgium.
Bliede Van den BroeckDepartment of Radiology and Nuclear Medicine, Ghent University Hospital, Ghent, Belgium.
Sigi HendrickxDepartment of Radiology and Nuclear Medicine, Ghent University Hospital, Ghent, Belgium.
Liv VeldemanDepartment of Human Structure and Repair, Ghent University, Ghent, Belgium.
Christel MontenDepartment of Human Structure and Repair, Ghent University, Ghent, Belgium.
Jens M DebackerMolecular Imaging and Therapy research group, Vrije Universiteit Brussel, Brussels, Belgium.
Hannelore DenysFaculty of Medicine and Health Science, Ghent University, Ghent, Belgium.
Menekse GökerDepartment of Obstetrics and Gynecology, Ghent University Hospital, Ghent, Belgium. menekse.goker@uzgent.be.

Funding

Agentschap voor Innovatie door Wetenschap en Technologie, Belgium (IM-IWT) HPC.2017.0515
6 · The paper itself

Abstract

Positive surgical margins in breast-conserving surgery (BCS) for breast cancer occur in 20% of cases, making intraoperative margin assessment (IMA) crucial to avoid re-operations. This study evaluated specimen PET-CT imaging for IMA in 41 patients undergoing BCS. Specimen PET-CT imaging was performed with the ß-CUBE/X-CUBE (MOLECUBES) or the AURA 10 (XEOS). Seven physicians, with varying experience, assessed margin status postoperatively as positive, close (≤1 mm), or negative using PET-CT images at 10 min acquisition time and low reconstructed [

Identifiers

PMID41006264
PMCPMC12474864

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.