Evidence map›Paper›PMID 41006233›Full record

ArticleNature communications2025

Correlates of risk of respiratory syncytial virus disease: a prospective cohort study.

Collrane Frivold, Sarah N Cox, Lea Starita, Tara M Babu, Katherine L Hoffman, Marco Carone, Christina M Lockwood, Jennifer L Kuntz, Richard A Mularski, Alexandra Varga and 19 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Collrane FrivoldDepartment of Medicine, University of Washington, Seattle, WA, USA. cfrivold@uw.edu.ORCID http://orcid.org/0000-0002-2000-5429
Sarah N CoxDepartment of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-2447-0504
Lea StaritaBrotman Baty Institute for Precision Medicine, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2870-5099
Tara M BabuDepartment of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-7093-4077
Katherine L HoffmanDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Marco CaroneDepartment of Biostatistics, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-2106-0953
Christina M LockwoodBrotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Jennifer L KuntzKaiser Permanente Center for Health Research, Portland, OR, USA.
Richard A MularskiKaiser Permanente Center for Health Research, Portland, OR, USA.
Alexandra VargaKaiser Permanente Center for Health Research, Portland, OR, USA.
Peter D HanDepartment of Biostatistics, University of Washington, Seattle, WA, USA.
Jonathan ReedDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-4425-7636
Eli A PiliperDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Shah A K Mohamed BakhashDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.
Alexander L GreningerDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-7443-0527
Erica ClarkDepartment of Medicine, University of Washington, Seattle, WA, USA.
Jeremy StoneDepartment of Medicine, University of Washington, Seattle, WA, USA.
Sally GrindstaffBrotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Cassandra L BoisvertKaiser Permanente Center for Health Research, Portland, OR, USA.
Neil YetzKaiser Permanente Center for Health Research, Portland, OR, USA.
Natalie K LoDepartment of Medicine, University of Washington, Seattle, WA, USA.
Tara L HatchieDepartment of Medicine, University of Washington, Seattle, WA, USA.
Grace MarshallDepartment of Medicine, University of Washington, Seattle, WA, USA.
Charles J WolockDepartment of Biostatistics and Computational Biology, University of Rochester, Rochester, NY, USA.ORCID http://orcid.org/0000-0003-3527-1102
Leora R FeldsteinCenters for Disease Control and Prevention, Atlanta, GA, USA.ORCID http://orcid.org/0000-0002-4430-6760
Ana A WeilDepartment of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-6170-4306
Janet A EnglundSeattle Children's Research Institute, Seattle, WA, USA.ORCID http://orcid.org/0000-0003-1134-4178
Allison L NalewayKaiser Permanente Center for Health Research, Portland, OR, USA.
Helen Y ChuDepartment of Medicine, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8502-9600

Funding

CDC HHS 75D30121C12297
6 · The paper itself

Abstract

Few population-based studies have evaluated the importance of pre-existing respiratory syncytial virus (RSV) antibody on RSV susceptibility among children and adults. We conducted a prospective, community-based cohort study among individuals aged 6 months-50 years in Oregon and Washington State, USA (June 2022-May 2023), with weekly symptom surveys and swab collection regardless of symptoms. Swabs were tested for RSV using RT-qPCR. Enrollment sera were tested for RSV prefusion F IgG binding (all participants) and neutralizing antibodies (pediatric participants). We detected 305 RSV illnesses among 3237 participants from 1188 households. Using proportional hazards regression, higher RSV binding antibody titers were associated with a lower estimated hazard of RSV among pediatric participants (hazard ratio=0.66 per 1-unit difference in log

Indexed as

Respiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdolescentAdultAntibodies, NeutralizingAntibodies, ViralChildChild, PreschoolFemaleHumansImmunoglobulin GInfantMaleMiddle AgedOregonProspective StudiesAntibodies, NeutralizingAntibodies, ViralImmunoglobulin G

Identifiers

PMID41006233
PMCPMC12475016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.