Evidence map›Paper›PMID 41005853›Full record

ArticleJACC. Case reports2025

Left Main Vasospasm Masquerading as Critical Stenosis Leading to Unnecessary Surgery.

Francesca Di Lenarda, Riccardo Terzi, Michele Gallazzi, Giovanni Monizzi, Emanuele Gallinoro, Pasquale Paolisso, Davide Marchetti, Edoardo Conte, Antonio L Bartorelli, Daniele Andreini

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesca Di LenardaDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy. Electronic address: francesca.dilenarda@gmail.com.
Riccardo TerziDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Michele GallazziDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Giovanni MonizziDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Emanuele GallinoroCardiology Unit, Sant'Andrea University Hospital, Rome, Italy.
Pasquale PaolissoCardiology Unit, Sant'Andrea University Hospital, Rome, Italy.
Davide MarchettiDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Edoardo ConteDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Antonio L BartorelliDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy.
Daniele AndreiniDivision of University Cardiology, IRCCS Ospedale Galeazzi Sant'Ambrogio, Milan, Italy; Department of Clinical and Biomedical Sciences, University of Milan, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVasospastic angina is a condition determined by epicardial coronary artery spasm, which is usually diagnosed from resting angina. CASE SUMMARY: A 62-year-old man was admitted for recurrent rest angina despite previous coronary artery bypass grafting and plain-old balloon angioplasty for multivessel disease. Coronary computed tomography angiography revealed occluded bypass grafts but nonsignificant coronary atherosclerosis, along with diffuse coronary ectasia and myocardial bridging. During invasive re-evaluation, intravascular ultrasound confirmed positive remodeling and intimal thickening, suggestive of vasospastic pathology. Critical, focal epicardial vasospasm during angiography triggered ventricular fibrillation, reversed by defibrillation. A transient right coronary artery occlusion with ST-elevation resolved with nitrates, highlighting the dynamic nature of the vasospasm. DISCUSSION: The case emphasizes the importance of considering coronary vasospasm in patients with ambiguous angiographic findings, the diagnostic and therapeutic role of intracoronary nitroglycerin, and the value of imaging in avoiding unnecessary revascularization. Careful pharmacologic testing and physiologic assessment are essential to distinguish functional vasospasm from fixed coronary disease, especially in left main involvement.

Indexed as

CABGCCTAIVUSvasospastic anginaventricular fibrillation

Identifiers

PMID41005853
PMCPMC12539429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.