Evidence map›Paper›PMID 41005851›Full record

ArticleJACC. Case reports2025

Echocardiography-Guided Percutaneous Paravalvular Mitral Leak Closure Without Fluoroscopy.

Kunjing Pang, Yutong Jiang, Yaoxing Lu, Xiangbin Pan

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in JACC. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kunjing PangDepartment of Echocardiography, National Center for Cardiovascular Disease, China, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yutong JiangDepartment of Echocardiography, National Center for Cardiovascular Disease, China, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yaoxing LuDepartment of Structural Heart Disease, National Center for Cardiovascular Disease, China, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xiangbin PanDepartment of Structural Heart Disease, National Center for Cardiovascular Disease, China, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China. Electronic address: panxiangbin@fuwaihospital.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTranscatheter paravalvular leak (PVL) closure is typically guided by fluoroscopy; however, fluoroscopic imaging may not always be available and can be unsuitable for select patient populations. FIRST-IN-HUMAN/EARLY REPORTS SUMMARY: We present the first-in-human case of successful PVL closure performed entirely under the guidance of three-dimensional transesophageal echocardiography (3D-TEE). DISCUSSION: The case demonstrates that 3D-TEE alone can effectively guide catheter navigation and device deployment, with optimal clinical outcomes. NOVELTY: To the best of our knowledge, this is the first reported experience of percutaneous PVL closure without fluoroscopy. TAKE-HOME MESSAGE: Fluoroscopy-free PVL closure is feasible under real-time 3D-TEE guidance and may be an alternative for select patients.

Indexed as

3D transesophageal echocardiographicparavalvular leakpercutaneous closure

Identifiers

PMID41005851
PMCPMC12539460

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.