Evidence map›Paper›PMID 41005770›Full record

ArticleBMJ open2025

Economic burden of moderate and severe anxiety and depression symptoms among adults in Saudi Arabia: evidence from a cross-sectional web panel survey.

Karen Arulsamy, Abdulrahman Alfaisal, Jyotika Puri, Mohammed Alluhidan, Yasmin Altwaijri, Abdulhameed Al-Habeeb, Mariam M Hamza, Volkan Cetinkaya, Eric Andrew Finkelstein

Abstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karen ArulsamyDuke-NUS Medical School, Singapore karen.arulsamy@duke-nus.edu.sg.ORCID http://orcid.org/0000-0002-6135-1598
Abdulrahman AlfaisalSaudi Health Council, Riyadh, Riyadh, Saudi Arabia.
Jyotika PuriUniversity of Melbourne, Melbourne, Victoria, Australia.
Mohammed AlluhidanSaudi Health Council, Riyadh, Riyadh, Saudi Arabia.
Yasmin AltwaijriKing Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0001-8826-3224
Abdulhameed Al-HabeebNational Center for Mental Health Promotion, Saudi Arabia Ministry of Health, Riyadh, Riyadh, Saudi Arabia.
Mariam M HamzaWorld Bank, Washington, District of Columbia, USA.ORCID http://orcid.org/0000-0002-5317-7067
Volkan CetinkayaWorld Bank, Washington, District of Columbia, USA.
Eric Andrew FinkelsteinDuke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0001-6443-9686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAnxiety and depression are among the top contributors to disability in the Kingdom of Saudi Arabia (KSA), but little is known about their economic impact. This study estimates the economic burden of moderate to severe symptoms of anxiety and depression among adults in KSA. DESIGN AND

settingA cross-sectional survey was administered via a web panel. Participants were asked to fill out the Patient Health Questionnaire-4 (PHQ-4) for themselves and on behalf of other household members to capture prevalence rates. Those who reported at least moderate symptoms of anxiety or depression filled out a longer survey with questions on healthcare utilisation and productivity losses due to symptoms. These responses were monetised using prevalence rates and population estimates to calculate per-person and total annual costs.

participantsPrevalence estimates are based on responses from 1164 participants on behalf of 3202 Saudi adults. Of these, 269 individuals with symptoms completed the longer survey. PRIMARY OUTCOME MEASURES: Prevalence of anxiety and depression; healthcare utilisation (medications, outpatient, inpatient) and productivity losses due to absenteeism and presenteeism.

resultsIn total, 26.2% reported at least moderate symptoms consistent with anxiety and/or depression. Among those with symptoms, direct healthcare costs due to anxiety and depression averaged Saudi riyal (SAR) 3431.95 per person annually. Indirect costs via absenteeism and presenteeism averaged SAR 9702.87 and SAR 24 577.28 per person assuming that anxiety and/or depression episodes last for 6 months. Summing up the healthcare costs and productivity losses yields a total annual economic burden of SAR 163.3 billion. Absenteeism accounts for 24.8% of this total (SAR 40.5 billion), presenteeism accounts for 62.8% (SAR 102.5 billion) and healthcare resource utilisation accounts for 12.4%(SAR 20.3 billion).

conclusionsThe overall prevalence of anxiety and depression in KSA is estimated at 26.2%. The economic burden associated with these symptoms amounts to SAR 163.3 billion or 4.1% of GDP. Absenteeism and presenteeism costs account for the vast majority of the total, but a large percentage (nearly 60%) also report emergency department visits and unplanned hospital admissions. Evidence-based interventions should be considered to address the health and economic burden of these conditions in KSA.

Indexed as

AnxietyCost of IllnessDepressionHealth Care CostsAbsenteeismAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPatient Acceptance of Health CarePresenteeismPrevalenceAnxiety disordersDepression & mood disordersHealth ServicesMENTAL HEALTH

Identifiers

PMID41005770
PMCPMC12481296

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.