Evidence map›Paper›PMID 41004654›Full record

ArticleBiomolecules & biomedicine2025

ICU admission delays: Impact on length of stay and long-term outcomes.

Ferhan Demirer Aydemir, Ozge Kurtkulagi, Bisar Ergun, Vecihe Bayrak, Ozlem Oner, Bilgin Comert, Ali Necati Gokmen, Volkan Hanci

Abstract read
In one paragraph

Article in Biomolecules & biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ferhan Demirer AydemirDepartment of Internal Medicine, Division of Intensive Care Medicine, Çanakkale Onsekiz Mart University Hospital, Çanakkale, Türkiye.
Ozge KurtkulagiDepartment of Internal Medicine, Faculty of Medicine, Çanakkale Onsekiz Mart University, Çanakkale, Türkiye.
Bisar ErgunDepartment of Internal Medicine, Division of Intensive Care Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Türkiye.
Vecihe BayrakDepartment of Internal Medicine, Division of Intensive Care Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Türkiye.
Ozlem OnerDepartment of Anesthesiology and Reanimation, Division of Intensive Care Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Türkiye.
Bilgin ComertDepartment of Internal Medicine, Division of Intensive Care Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Türkiye.
Ali Necati GokmenDepartment of Anesthesiology and Reanimation, Division of Intensive Care Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Türkiye.
Volkan HanciDepartment of Anesthesiology and Reanimation, Division of Intensive Care Medicine, Dokuz Eylul University Faculty of Medicine, Izmir, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Delays in intensive care unit (ICU) admissions are prevalent in overcrowded hospitals and can adversely affect patient outcomes. However, the extent of this impact, particularly beyond short-term mortality, remains unclear. We hypothesized that ICU admission delays exceeding 6 hours after consultation would independently increase 90-day mortality and prolong ICU length of stay. We conducted a retrospective analysis of data from 273 adult patients admitted to the ICU of a tertiary university hospital between January and December 2019. Patients were stratified into two groups: early admission (≤6 hours) and delayed admission (>6 hours). Multivariate Cox regression was employed to identify independent predictors of mortality. Delayed ICU admission was observed in 72.8% of patients. Although delayed admission was not independently associated with increased mortality in the multivariate analysis (HR: 0.88; 95% CI: 0.61-1.27), it was significantly correlated with prolonged ICU length of stay and higher 90-day mortality in the univariate analysis (p = 0.039), with no significant difference in vasopressor-free days (p = 0.809). In our assessment of independent mortality predictors, we found that patients with higher APACHE-II and Charlson scores experienced longer delays in ICU transfer. Additionally, respiratory and circulatory failure at admission were independently associated with increased mortality (HR: 2.17; 95% CI: 1.51-3.12). While early ICU admission did not independently predict mortality, it was linked to extended ICU stays, an increased treatment burden, and adverse long-term outcomes. These findings underscore the necessity of refining triage processes and evaluating baseline patient severity when interpreting the impact of ICU admission timing on outcomes.

Indexed as

Intensive Care UnitsLength of StayPatient AdmissionAdultAgedAPACHEFemaleHospital MortalityHumansMaleMiddle AgedRetrospective StudiesTime Factors

Identifiers

PMID41004654
PMCPMC12533816

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.