Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
21 authors.
Young-Il KimCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-0145-7382
Seung-Gyu JangVirus Research Resource Center, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0001-9316-1652
Woohyun KwonCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0009-0006-9023-0273
Jaemoo KimCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0009-0003-4216-8397
Dongbin ParkCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0001-5289-1034
Isaac ChoiCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0009-0008-0798-8193
Jeong Ho ChoiCollege of Medicine and Medical Research Institute, Chungbuk National University, 1 Chungdae-ro, Seowon-gu, Cheongju 28644, Republic of Korea.ORCID 0000-0002-9483-4780
Juryeon GilCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-9415-0688
Mina YuCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0003-3311-7515
Boyeong JeongCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0009-0008-2541-0328
Eun-Ha KimVirus Research Resource Center, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0003-1443-3416
Se-Mi KimCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0001-7932-1381
Hyunjoon KimCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-0207-1190
Jae-Woo AhnCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-2706-5010
Suhee HwangCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-1028-1323
Seo-Young HeoCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0009-0002-7486-4816
Mark Anthony B CaselCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-8313-4076
Rare RollonCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-8428-1713
Thomas FabrizioDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-8960-0728
Richard J WebbyDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-4397-7132
Young Ki ChoiCenter for Study of Emerging and Re-emerging Viruses, Korea Virus Research Institute, Institute for Basic Science, Daejeon 34126, Republic of Korea.ORCID 0000-0002-0872-0147
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
The 2022 North American outbreak of 2.3.4.4b H5N1 avian influenza virus revealed substantial mammalian adaptation and pathogenicity, yet mechanisms remain unclear. To address this knowledge gap, we investigated the North American H5N1 strain (GA/W22-145E/22), which demonstrated unique immune cell-mediated systemic dissemination, neuroinvasion, and 100% mortality in ferrets, unlike the nonlethal Eurasian strain (KR/W811/21). Genomic and reverse genetics studies identified PB2
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
PB2 and NP of North American H5N1 virus drive immune cell replication and systemic infections. · full record | OpenQuestion