Trial reportPloS one2025
Identifying robust predictors of treatment response in trauma-affected refugees: Results from a randomised controlled trial.
Trial report in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02761161 (Treatment of Sleep Disturbances in Trauma-affected Refugees), which is not on this map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Treatment of Sleep Disturbances in Trauma-affected Refugees: A Randomised Controlled Trial
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGiven the high prevalence of trauma-related mental health problems in a growing population of refugees, identifying robust predictors of treatment outcome can optimize treatment strategies and resource allocation. The current study aimed to examine the robustness of predictors from seven previous predictor studies at the Competence Centre for Transcultural Psychiatry (CTP).
methodsWe studied if predictors from previous studies could be replicated in a sample of 219 refugees with PTSD who participated in a new distinct study conducted at CTP. We included all variables previously found to be significantly related to treatment response, as measured via the Harvard Trauma Questionnaire (HTQ) and the Hamilton Depression Scale (HAM-D). We categorised the variables as sociodemographic factors, CTP predictor index items, and baseline assessment scores. We performed regression analyses with one exposure variable at a time, controlling for baseline assessment scores corresponding to the dependent variable. We also conducted multiple linear regression analyses to examine the variance explained in total by the identified significant predictor variables.
resultsThe study successfully replicated several predictors of treatment response for PTSD and depression, including a high understanding of therapy concepts, acceptability of psychological treatment, ability to reflect, motivation for active participation and cognitive resources, as well as low baseline pain levels. The findings replicated a U-shaped relationship between age and treatment response for depression, indicating better outcomes for younger participants and those over 60. Multiple regression analyses explained 28% and 39% of the variance in the PTSD (HTQ) and depression (HAM-D) treatment responses, respectively.
conclusionsThis study contributes to the understanding of treatment response predictors in trauma-affected refugees by replicating findings from previous research in a new sample. It highlights the importance of modifiable factors, such as psychotherapy readiness, and underscores the necessity for tailored interventions to enhance treatment efficacy. As the global refugee crisis grows, the insights from this research can inform mental health strategies, ultimately improving care for this vulnerable population. Future research should continue to investigate modifiable predictors to further enhance treatment outcomes.
trial registrationClinicalTrials.gov NCT02761161.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.