Evidence map›Paper›PMID 41004416›Full record

ArticleJournal of the International Association of Providers of AIDS Care

A Mixed-Methods Pilot Study to Explore the Feasibility and Acceptability of SMS Reminders to Improve Adverse Drug Reaction Reporting among Adults on ART in Tanzania.

Lyidia Vedasto Masika, Naomi Emmanuel, Tumaini Mirai, Gloria Nyanungu, Mary Shirima, Marion Sumari-de Boer, Rehema Maro, Benson Mtesha, Kennedy Ngowi

Abstract read
In one paragraph

Article in Journal of the International Association of Providers of AIDS Care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Adapting SMS-Based Pharmacovigilance Strategies From Tanzania to the Philippine ART Program.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lyidia Vedasto MasikaData Management Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.ORCID 0000-0002-1623-1634
Naomi EmmanuelData Management Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Tumaini MiraiDepartment of Pharmacy, Child Centred Family Care Clinic, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.ORCID 0009-0009-9685-7765
Gloria NyanunguDepartment of Pharmacy, Child Centred Family Care Clinic, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Mary ShirimaCare and Treatment Unit, Majengo Health Centre, Moshi, Tanzania.
Marion Sumari-de BoerData Management Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.ORCID 0000-0002-5433-0406
Rehema MaroData Management Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.ORCID 0000-0002-8310-6665
Benson MteshaData Management Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.
Kennedy NgowiData Management Unit, Kilimanjaro Clinical Research Institute, Moshi, Tanzania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionIn Sub-Saharan Africa, there are knowledge gaps on adverse drug reactions (ADRs) of antiretroviral treatment. This study examined the acceptability and feasibility of short message service (SMS) to increase awareness about the importance of reporting ADRs among people living with HIV (PLHIV) in Tanzania.MethodsIn this pilot study, PLHIV consented to participate and received SMS asking about their health. Responses to messages generated a flow of follow-up questions through SMS that determined the presence of ADRs. Technical feasibility was calculated based on the percentage of SMS sent and delivered, and acceptability was based on SMS replies. We conducted focus group discussions and in-depth interviews with participants and healthcare workers to understand experiences and acceptability of the system. Qualitative data were analyzed using thematic content analysis, and quantitative data were summarized using descriptive analyses.ResultsNinety-two participants were recruited. Sixty-two (67.4%) were women. The mean age was 42 years (SD ± 12). Among the sent SMS, 100 (95.2%) were replied to. Themes identified through qualitative data were: high motivation to report ADR, well-understood SMS content, no concerns about unwanted disclosure, and network difficulties.ConclusionThe SMS system is a user-friendly intervention and highly accepted based on qualitative data among PLHIV in Tanzania.

Indexed as

Adverse Drug Reaction Reporting SystemsAnti-HIV AgentsAnti-Retroviral AgentsDrug-Related Side Effects and Adverse ReactionsHIV InfectionsReminder SystemsText MessagingAdultFeasibility StudiesFemaleFocus GroupsHumansMaleMiddle AgedPilot ProjectsQualitative ResearchAnti-HIV AgentsAnti-Retroviral Agentsadverse drug reactionsdigital interventionsPLHIVSMS interventions

Identifiers

PMID41004416
PMCPMC12475335

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.