Evidence map›Paper›PMID 41004199›Full record

ArticleJournal of managed care & specialty pharmacy2025

AMCP Market Insights: Navigating the rapidly changing landscape of ER+/HER2- metastatic breast cancer.

Bridget Flavin, Denise Wolff, Laura Bobolts, Gaurang Gandhi, Ryan Haumschild, Neil Iyengar, Michael Kobernick, Rebecca Lich, Bhavesh Shah

Abstract read
In one paragraph

Article in Journal of managed care & specialty pharmacy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bridget FlavinConnected Content, Ltd., Boulder, CO.
Denise WolffDenise & Co., LLC, Duluth, MN.
Laura BoboltsOncoHealth, Plantation, FL.
Gaurang GandhiPrime Therapeutics/MagellanRx, Eagan, MN.
Ryan HaumschildEmory Healthcare and Winship Cancer Institute, Atlanta, GA.
Neil IyengarMemorial Sloan Kettering Cancer Center, New York, NY.
Michael KobernickBlue Cross Blue Shield of Michigan, Huntington Woods.
Rebecca LichLockton, Denver, CO.
Bhavesh ShahBoston Medical Center, MA.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Breast cancer is the most common cancer diagnosed in women in the United States, and its impact on both patients and their caregivers, particularly in advanced or metastatic disease, is substantial. Additionally, for the most common breast cancer subtype (estrogen receptor [ER]+/human endothelial growth factor receptor 2 [HER2]-), the treatment landscape for metastatic disease is continuously evolving, making appropriate therapy sequencing challenging. To discuss navigating the rapidly changing landscape of ER+/HER2- metastatic breast cancer (mBC), AMCP Market Insights virtually convened an expert panel of managed care stakeholders in February 2025. Key insights from the discussion on ER+/HER2- mBC included addressing the patient care journey, maintaining high-quality care, managing the impact to payers, evaluating new and emerging therapies, and looking toward the future. Suggested payer best practices in ER+/HER2- mBC also emerged from the discussion.

Indexed as

Breast NeoplasmsErb-b2 Receptor Tyrosine KinasesManaged Care ProgramsFemaleHumansNeoplasm MetastasisReceptors, EstrogenUnited StatesERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesReceptors, Estrogen

Identifiers

PMID41004199
PMCPMC12467767

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.