Evidence map›Paper›PMID 41004108›Full record

ReviewAdvances in neurobiology2025

HIT Your Brain: Neuron and New Run.

Min-Chul Lee, Hideaki Soya

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances in neurobiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Min-Chul LeeDepartment of Sports Medicine, College of Health Science, CHA University, Pocheon, South Korea. mclee@cha.ac.kr.
Hideaki SoyaLaboratory of Exercise Biochemistry and Neuroendocrinology, Institute of Health and Sport Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of physical activity in neuroscience is gaining increasing recognition. The question arises: What is the specific focus of exercise, and what factors contribute to the observed benefits of exercise in neuroscience? Various forms of exercise have been examined across physiological, psychological, and biochemical experiments within neuroscience. Still, there is a need for greater clarity to identify optimal exercise conditions, including the FITT-VP variables (frequency, intensity, type, and time).This chapter aims to shed light on the positive impacts of high-intensity training (HIT) exercises in facilitating physiological adaptation and exploring the newfound role in brain functions. Key areas explored include (1) exercise neuroscience at the structural level involving synaptic plasticity and neurogenesis; (2) functional level concerning behavioral development; and (3) molecular level addressing potential mechanisms underlying exercise-induced brain plasticity.Overall, high-intensity training emerges as a more cost-effective method for enhancing physiological adaptations, including improvements in aerobic capacity. Additionally, it has been shown to influence brain functions such as hippocampus-dependent learning and memory positively. These findings offer valuable insights into the practicality of high-intensity training for performance improvement and suggest directions for future research.

Indexed as

Adaptation, PhysiologicalBrainExerciseNeurogenesisNeuronal PlasticityNeuronsAnimalsHumansBrain-derived neurotrophic factor (BDNF)Brain functionsHigh-intensity interval training (HIT)HippocampusResistant wheel running (RWR)

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.