Evidence map›Paper›PMID 41003979›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Optimized detection of ESBL producers, carbapenemase producers, and VRE from rectal swabs using enrichment broth for superior screening sensitivity.

Dominique S Blanc, Massiha Kamyar, Patrice Nordmann, Laurent Poirel, Gilbert Greub

Abstract readEvaluation Study
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dominique S BlancInfection Prevention and Control Unit, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. dominique.blanc@chuv.ch.
Massiha KamyarInfection Prevention and Control Unit, Infectious Diseases Service, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.
Patrice NordmannSwiss National Reference Center for Emerging Antibiotic Resistance, Fribourg, Switzerland.
Laurent PoirelSwiss National Reference Center for Emerging Antibiotic Resistance, Fribourg, Switzerland.
Gilbert GreubSwiss National Reference Center for Emerging Antibiotic Resistance, Fribourg, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the added value of using enrichment broths for improving the detection of multidrug-resistant (MDR) bacteria-VRE, ESBL producers, and carbapenemase-producing organisms (CPOs)-from rectal swabs. Comparing direct plating to enrichment-based methods significantly increased detection sensitivity, especially for CPOs (from 17 to 27 cases, a 58.8% increase). Detection rates for ESBL producers and VRE also improved significantly (by 20%). Pre-enrichment is therefore a valuable addition to routine MDR bacteria screening protocols, which is particularly useful when high accuracy is needed for prevention and infection control as well as for outbreak management.

Indexed as

Bacterial ProteinsBacteriological Techniquesbeta-LactamasesRectumVancomycin-Resistant EnterococciCulture MediaDrug Resistance, Multiple, BacterialHumansMass ScreeningSensitivity and SpecificityBacterial Proteinsbeta-LactamasescarbapenemaseCulture Media

Identifiers

PMID41003979
PMCPMC12753533

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.